The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos

BACKGROUND Post-zygotic chromosome segregation errors are very common in human embryos after in vitro fertilization, resulting in mosaic embryos. However, the significance of mosaicism for the developmental potential of early embryos is unknown. We assessed chromosomal constitution and development o...

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Veröffentlicht in:	Human reproduction (Oxford) 2010-08, Vol.25 (8), p.1916-1926
Hauptverfasser:	Santos, Margarida Avo, Teklenburg, Gijs, Macklon, Nick S., Van Opstal, Diane, Schuring-Blom, G. Heleen, Krijtenburg, Pieter-Jaap, de Vreeden-Elbertse, Johanna, Fauser, Bart C., Baart, Esther B.
Format:	Artikel
Sprache:	eng
Schlagworte:	aneuploidies Biological and medical sciences Blastocyst - ultrastructure chromosomal mosaicism Chromosomes, Human - chemistry Chromosomes, Human - ultrastructure Coculture Techniques Embryo Culture Techniques Embryonic Development - genetics FISH Gynecology. Andrology. Obstetrics human embryos Humans In Situ Hybridization, Fluorescence Medical sciences Mosaicism - embryology
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