Mosquitocidal triterpenes from the stem of Duranta repens

Mosquitocidal triterpenes from the stem of Duranta repens

Two triterpenes, β-amyrin and 12-oleanene 3β, 21β-diol, were isolated as a mixture from the chloroform soluble fraction of an ethanol extract of Duranta repens Linn (Verbenaceae) stem. The structures of the two compounds were confirmed by analysis of their IR, 1H-NMR, 13C-NMR and LC-MS spectral data...

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Veröffentlicht in:Pharmaceutical biology 2010-03, Vol.48 (3), p.264-268
Hauptverfasser: Nikkon, Farjana, Salam, Kazi Abdus, Yeasmin, Tanzima, Mosaddik, Ashik, Khondkar, Proma, Haque, M. Ekramul
Format: Artikel
Sprache:eng
Schlagworte:
12-oleanene 3β
21β-diol
Animals
Chromatography, High Pressure Liquid
Culex - growth & development
Duranta repens Linn
Insecticide Resistance
Insecticides - analysis
Insecticides - chemistry
Insecticides - isolation & purification
Larva
Lethal Dose 50
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Structure
Mosquito Control
Mosquitocidal
Oleanolic Acid - analogs & derivatives
Oleanolic Acid - analysis
Oleanolic Acid - chemistry
Oleanolic Acid - isolation & purification
Plant Extracts - chemistry
Plant Stems - chemistry
Reproducibility of Results
Spectrophotometry, Infrared
Time Factors
Triterpenes - analysis
Triterpenes - chemistry
Triterpenes - isolation & purification
Verbenaceae - chemistry
β-amyrin
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Beschreibung
Zusammenfassung:Two triterpenes, β-amyrin and 12-oleanene 3β, 21β-diol, were isolated as a mixture from the chloroform soluble fraction of an ethanol extract of Duranta repens Linn (Verbenaceae) stem. The structures of the two compounds were confirmed by analysis of their IR, 1H-NMR, 13C-NMR and LC-MS spectral data. The mixture of β-amyrin and 12-oleanene 3β, 21β-diol (compound 1) was highly effective against the larvae of the mosquito, Culex quinquefasciatus Say (Diptera: Culicidae), as a mosquitocide.
ISSN:1388-0209
1744-5116
DOI:10.3109/13880200903096570