When the first antiepileptic drug fails in a patient with juvenile myoclonic epilepsy
Juvenile myoclonic epilepsy is one of the most common types of epilepsy seen in an adult epilepsy clinic. Most patients have a good prognosis, particularly when treated with valproate, but a significant minority are more difficult to treat. In this article, we will focus on a management strategy whe...
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Veröffentlicht in: | Practical Neurology 2010-08, Vol.10 (4), p.208-218 |
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description | Juvenile myoclonic epilepsy is one of the most common types of epilepsy seen in an adult epilepsy clinic. Most patients have a good prognosis, particularly when treated with valproate, but a significant minority are more difficult to treat. In this article, we will focus on a management strategy when the initial antiepileptic drug is unsuccessful and outline an approach that translates directly to the clinic. |
doi_str_mv | 10.1136/jnnp.2010.217976 |
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Cerebral palsy</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Myoclonic Epilepsy, Juvenile - drug therapy</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Treatment Failure</subject><issn>1474-7758</issn><issn>1474-7766</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqF0M-L1DAUB_Agirs7evckAZE9SNf8TnpcBnWFcfXgqreQSRMntU1r0qrz35uh4whePOWF93mPxxeAJxhdYUzFyzbG8Yqg8iVY1lLcA-eYSVZJKcT9U83VGbjIuUWoIFo_BGcECSY5kefg7vPORTjtHPQh5QmaOAU3hs6NU7CwSfNX6E3oMgwRGjia0o0T_BmmHWznHy4WCfv9YLshFr9M5v0j8MCbLrvHx3cF7l6_-ri-qTbv37xdX2-qLWV8qoizWNW2IUIaSoUV3DvMuXGqoc56hVTtmVcc1ZRj3qBGqi03tcUOIycbRlfgctk7puH77PKk-5Ct6zoT3TBnLSlDCClykM_-ke0wp1iO01gqLLhSRBaFFmXTkHNyXo8p9CbtNUb6kLg-JK4Piesl8TLy9Lh43vauOQ38ibiA50dgsjWdTybakP86ihRjZfcKVIsLeXK_Tn2TvmkhqeT69tNaq80t-fLhXa1vin-x-G3f_v_M34FnpgQ</recordid><startdate>201008</startdate><enddate>201008</enddate><creator>Nicolson, Andrew</creator><creator>Marson, Anthony G</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>201008</creationdate><title>When the first antiepileptic drug fails in a patient with juvenile myoclonic epilepsy</title><author>Nicolson, Andrew ; Marson, Anthony G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b345t-2ec189cd267a336c65fe155ae8d3ecf8089f4f85093515d0d78b5a9c1e10e7d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Anticonvulsants - adverse effects</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Clinical Protocols</topic><topic>Disease Management</topic><topic>Drug Resistance - physiology</topic><topic>Headache. 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subjects | Adolescent Anticonvulsants - adverse effects Anticonvulsants - therapeutic use Biological and medical sciences Child Clinical Protocols Disease Management Drug Resistance - physiology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Medical sciences Myoclonic Epilepsy, Juvenile - drug therapy Nervous system (semeiology, syndromes) Neurology Treatment Failure |
title | When the first antiepileptic drug fails in a patient with juvenile myoclonic epilepsy |
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