L1 Cell Adhesion Molecule Is a Novel Therapeutic Target in Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC), a highly malignant hepatobiliary cancer, has a poor prognosis and is refractory to conventional therapies. The aim of this study is to discover a novel molecular target for the treatment of ICC. To discover novel cancer-associated membrane antigens expressed in...

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Veröffentlicht in:	Clinical cancer research 2010-07, Vol.16 (14), p.3571-3580
Hauptverfasser:	MIN, Jeong-Ki, KIM, Jin-Man, YOUNG KWAN LEE, KIM, Bong-Hui, YEON SUNG SON, HONG SEO CHOI, LIM, Nam-Kyu, KIM, Dae-Ghon, HYO JEONG HONG, SHENGJIN LI, JUNG WHOI LEE, YOON, Hyunho, CHUN JEIH RYU, SOUNG HOO JEON, LEE, Jae-Hyek, JIN YOUNG KIM, HEE KWAN YOON
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - immunology Antigen-Antibody Reactions Antineoplastic agents Apoptosis - immunology Bile Duct Neoplasms - immunology Bile Duct Neoplasms - pathology Bile Ducts, Intrahepatic - immunology Bile Ducts, Intrahepatic - pathology Biological and medical sciences Blotting, Western Cell Movement Cell Proliferation Cholangiocarcinoma - immunology Cholangiocarcinoma - pathology Disease Progression Gastroenterology. Liver. Pancreas. Abdomen Humans Immunohistochemistry Liver Neoplasms - immunology Liver Neoplasms - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Mice Mice, Nude Neoplasm Transplantation Neoplasms, Experimental - immunology Neural Cell Adhesion Molecule L1 - biosynthesis Neural Cell Adhesion Molecule L1 - immunology Pharmacology. Drug treatments Tumor Cells, Cultured Tumors
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