Marek's disease virus reactivation from latency: changes in gene expression at the origin of replication

Marek's disease is a contagious lymphoma of chickens caused by Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes latency within and transforms chicken CD4+ T-cells. Transformed T-cells are seen as skin leukosis or as lymphomas in visceral organs. A major fo...

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Veröffentlicht in:	Poultry science 2003-06, Vol.82 (6), p.893-898
Hauptverfasser:	Parcells, M.S, Arumugaswami, V, Prigge, J.T, Pandya, K, Dienglewicz, R.L
Format:	Artikel
Sprache:	eng
Schlagworte:	animal genetics Animals Apoptosis CD4-Positive T-Lymphocytes - virology chickens Gallid herpesvirus 2 gene expression Gene Expression Regulation Interleukin-8 - genetics Kinetics latent period Mardivirus - genetics Mardivirus - pathogenicity Marek Disease nucleotide sequences open reading frames pathogenesis phosphoprotein 38 Phosphoproteins - genetics Poultry poultry diseases Poultry Diseases - genetics Poultry Diseases - virology replication origin transcription (genetics) Transcription, Genetic Virus Replication
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