Comparison of 30-day outcomes after emergency general surgery procedures: Potential for targeted improvement
Background Patients who undergo emergency operations represent a high-risk population and have been shown to have a high risk of poor outcomes. Little is known, however, about the variability in the quality of emergency general surgical care across hospitals or within hospitals across different proc...
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creator | Ingraham, Angela M., MD Cohen, Mark E., PhD Bilimoria, Karl Y., MD, MS Raval, Mehul V., MD Ko, Clifford Y., MD, MS, MSHS Nathens, Avery B., MD, PhD Hall, Bruce L., MD, PhD, MBA |
description | Background Patients who undergo emergency operations represent a high-risk population and have been shown to have a high risk of poor outcomes. Little is known, however, about the variability in the quality of emergency general surgical care across hospitals or within hospitals across different procedures. The objectives of this study were to identify risk factors associated with adverse events, to compare 30-day outcomes after 3 common emergency general surgery procedures within and across hospitals, and thus, to determine whether the quality of emergency surgical care is procedure-dependent or intrinsic to other aspects of the hospital environment. Methods Patients who underwent emergency appendectomy, cholecystectomy, or colorectal resection at 95 hospitals that submitted at least 20 of each procedure were identified in the 2005–2008 American College of Surgeons National Surgical Quality Improvement Project database. Outcomes of interest included 30-day overall morbidity and serious morbidity/mortality. Step-wise logistic regression generated patient-level predicted probabilities of an outcome. Based on the expected probabilities, observed to expected (O/E) ratios for each outcome, after each of the 3 procedures, were calculated for each hospital. Hospitals were divided into terciles based on O/E ratios. The agreement on hospital outcomes performance for overall morbidity and serious morbidity/mortality after appendectomy, cholecystectomy, and colorectal resection was assessed using weighted kappa statistics. Results Of the 30,788 appendectomies, 1,984 (6.44%) patients had any morbidity, and 1,140 (3.70%) patients had a serious morbidity or died. Of the 5,824 cholecystectomies, 503 (8.64%) patients had any morbidity, and 371 (6.37%) patients had a serious morbidity or died. Of the 8,990 colorectal resections, 4,202 (46.74%) patients had any morbidity, and 3,736 (41.56%) patients had a serious morbidity or died. For overall morbidity, O/E ratios for appendectomy ranged from 0.26 to 2.36; O/E ratios for cholecystectomy ranged from 0 to 3.04; O/E ratios for colorectal resection ranged from 0.45 to 1.51. For serious morbidity/mortality, O/E ratios for appendectomy ranged from 0.23 to 2.54; O/E ratios for cholecystectomy ranged from 0 to 4.28; O/E ratios for colorectal resection ranged from 0.59 to 1.75. Associations of risk-adjusted hospital outcomes based on tercile rank between procedures demonstrated slight but significant agreement for both overall morb |
doi_str_mv | 10.1016/j.surg.2010.05.009 |
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Little is known, however, about the variability in the quality of emergency general surgical care across hospitals or within hospitals across different procedures. The objectives of this study were to identify risk factors associated with adverse events, to compare 30-day outcomes after 3 common emergency general surgery procedures within and across hospitals, and thus, to determine whether the quality of emergency surgical care is procedure-dependent or intrinsic to other aspects of the hospital environment. Methods Patients who underwent emergency appendectomy, cholecystectomy, or colorectal resection at 95 hospitals that submitted at least 20 of each procedure were identified in the 2005–2008 American College of Surgeons National Surgical Quality Improvement Project database. Outcomes of interest included 30-day overall morbidity and serious morbidity/mortality. Step-wise logistic regression generated patient-level predicted probabilities of an outcome. Based on the expected probabilities, observed to expected (O/E) ratios for each outcome, after each of the 3 procedures, were calculated for each hospital. Hospitals were divided into terciles based on O/E ratios. The agreement on hospital outcomes performance for overall morbidity and serious morbidity/mortality after appendectomy, cholecystectomy, and colorectal resection was assessed using weighted kappa statistics. Results Of the 30,788 appendectomies, 1,984 (6.44%) patients had any morbidity, and 1,140 (3.70%) patients had a serious morbidity or died. Of the 5,824 cholecystectomies, 503 (8.64%) patients had any morbidity, and 371 (6.37%) patients had a serious morbidity or died. Of the 8,990 colorectal resections, 4,202 (46.74%) patients had any morbidity, and 3,736 (41.56%) patients had a serious morbidity or died. For overall morbidity, O/E ratios for appendectomy ranged from 0.26 to 2.36; O/E ratios for cholecystectomy ranged from 0 to 3.04; O/E ratios for colorectal resection ranged from 0.45 to 1.51. For serious morbidity/mortality, O/E ratios for appendectomy ranged from 0.23 to 2.54; O/E ratios for cholecystectomy ranged from 0 to 4.28; O/E ratios for colorectal resection ranged from 0.59 to 1.75. Associations of risk-adjusted hospital outcomes based on tercile rank between procedures demonstrated slight but significant agreement for both overall morbidity (weighted kappa between 0.20 and 0.22) and serious morbidity/mortality (weighted kappa between 0.18 and 0.22). Despite this, 7 (7.4%) hospitals for overall morbidity and 9 (9.5%) hospitals for serious morbidity/mortality were rated in the highest (best) tercile for all procedures. Eight (8.4%) hospitals for overall morbidity and 8 (8.4%) hospitals for serious morbidity/mortality were rated in the lowest tercile for all procedures. Conclusion Emergency general surgery procedures, particularly colorectal resections, were associated with substantial 30-day overall morbidity and serious morbidity/mortality. Most hospitals did not have consistent risk-adjusted outcomes across all 3 procedures, but for a substantive minority of institutions (7–10%), good or bad performance was generalizable across procedures. Individual hospitals should examine their procedure-specific outcomes after emergency general surgery operations to focus quality improvement initiatives appropriately.</description><identifier>ISSN: 0039-6060</identifier><identifier>EISSN: 1532-7361</identifier><identifier>DOI: 10.1016/j.surg.2010.05.009</identifier><identifier>PMID: 20633727</identifier><identifier>CODEN: SURGAZ</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject><![CDATA[Adolescent ; Adult ; Aged ; Appendectomy - adverse effects ; Appendectomy - mortality ; Appendectomy - statistics & numerical data ; Biological and medical sciences ; Cholecystectomy - adverse effects ; Cholecystectomy - mortality ; Cholecystectomy - statistics & numerical data ; Databases, Factual ; Digestive System Surgical Procedures - adverse effects ; Digestive System Surgical Procedures - mortality ; Digestive System Surgical Procedures - statistics & numerical data ; Emergency Service, Hospital - statistics & numerical data ; Female ; General aspects ; Humans ; Male ; Medical sciences ; Middle Aged ; Postoperative Complications - epidemiology ; Postoperative Complications - mortality ; Postoperative Complications - prevention & control ; Risk Adjustment ; Risk Factors ; Surgery ; Surgical Procedures, Operative - adverse effects ; Surgical Procedures, Operative - mortality ; Surgical Procedures, Operative - statistics & numerical data ; Time Factors ; Treatment Outcome ; United States - epidemiology ; Young Adult]]></subject><ispartof>Surgery, 2010-08, Vol.148 (2), p.217-238</ispartof><rights>Mosby, Inc.</rights><rights>2010 Mosby, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c506t-276518797c89de80243ef91d6a001f926f255068fe60c2b626890d3db3e01d863</citedby><cites>FETCH-LOGICAL-c506t-276518797c89de80243ef91d6a001f926f255068fe60c2b626890d3db3e01d863</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0039606010002692$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23066397$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20633727$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ingraham, Angela M., MD</creatorcontrib><creatorcontrib>Cohen, Mark E., PhD</creatorcontrib><creatorcontrib>Bilimoria, Karl Y., MD, MS</creatorcontrib><creatorcontrib>Raval, Mehul V., MD</creatorcontrib><creatorcontrib>Ko, Clifford Y., MD, MS, MSHS</creatorcontrib><creatorcontrib>Nathens, Avery B., MD, PhD</creatorcontrib><creatorcontrib>Hall, Bruce L., MD, PhD, MBA</creatorcontrib><title>Comparison of 30-day outcomes after emergency general surgery procedures: Potential for targeted improvement</title><title>Surgery</title><addtitle>Surgery</addtitle><description>Background Patients who undergo emergency operations represent a high-risk population and have been shown to have a high risk of poor outcomes. Little is known, however, about the variability in the quality of emergency general surgical care across hospitals or within hospitals across different procedures. The objectives of this study were to identify risk factors associated with adverse events, to compare 30-day outcomes after 3 common emergency general surgery procedures within and across hospitals, and thus, to determine whether the quality of emergency surgical care is procedure-dependent or intrinsic to other aspects of the hospital environment. Methods Patients who underwent emergency appendectomy, cholecystectomy, or colorectal resection at 95 hospitals that submitted at least 20 of each procedure were identified in the 2005–2008 American College of Surgeons National Surgical Quality Improvement Project database. Outcomes of interest included 30-day overall morbidity and serious morbidity/mortality. Step-wise logistic regression generated patient-level predicted probabilities of an outcome. Based on the expected probabilities, observed to expected (O/E) ratios for each outcome, after each of the 3 procedures, were calculated for each hospital. Hospitals were divided into terciles based on O/E ratios. The agreement on hospital outcomes performance for overall morbidity and serious morbidity/mortality after appendectomy, cholecystectomy, and colorectal resection was assessed using weighted kappa statistics. Results Of the 30,788 appendectomies, 1,984 (6.44%) patients had any morbidity, and 1,140 (3.70%) patients had a serious morbidity or died. Of the 5,824 cholecystectomies, 503 (8.64%) patients had any morbidity, and 371 (6.37%) patients had a serious morbidity or died. Of the 8,990 colorectal resections, 4,202 (46.74%) patients had any morbidity, and 3,736 (41.56%) patients had a serious morbidity or died. For overall morbidity, O/E ratios for appendectomy ranged from 0.26 to 2.36; O/E ratios for cholecystectomy ranged from 0 to 3.04; O/E ratios for colorectal resection ranged from 0.45 to 1.51. For serious morbidity/mortality, O/E ratios for appendectomy ranged from 0.23 to 2.54; O/E ratios for cholecystectomy ranged from 0 to 4.28; O/E ratios for colorectal resection ranged from 0.59 to 1.75. Associations of risk-adjusted hospital outcomes based on tercile rank between procedures demonstrated slight but significant agreement for both overall morbidity (weighted kappa between 0.20 and 0.22) and serious morbidity/mortality (weighted kappa between 0.18 and 0.22). Despite this, 7 (7.4%) hospitals for overall morbidity and 9 (9.5%) hospitals for serious morbidity/mortality were rated in the highest (best) tercile for all procedures. Eight (8.4%) hospitals for overall morbidity and 8 (8.4%) hospitals for serious morbidity/mortality were rated in the lowest tercile for all procedures. Conclusion Emergency general surgery procedures, particularly colorectal resections, were associated with substantial 30-day overall morbidity and serious morbidity/mortality. Most hospitals did not have consistent risk-adjusted outcomes across all 3 procedures, but for a substantive minority of institutions (7–10%), good or bad performance was generalizable across procedures. Individual hospitals should examine their procedure-specific outcomes after emergency general surgery operations to focus quality improvement initiatives appropriately.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Appendectomy - adverse effects</subject><subject>Appendectomy - mortality</subject><subject>Appendectomy - statistics & numerical data</subject><subject>Biological and medical sciences</subject><subject>Cholecystectomy - adverse effects</subject><subject>Cholecystectomy - mortality</subject><subject>Cholecystectomy - statistics & numerical data</subject><subject>Databases, Factual</subject><subject>Digestive System Surgical Procedures - adverse effects</subject><subject>Digestive System Surgical Procedures - mortality</subject><subject>Digestive System Surgical Procedures - statistics & numerical data</subject><subject>Emergency Service, Hospital - statistics & numerical data</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - mortality</subject><subject>Postoperative Complications - prevention & control</subject><subject>Risk Adjustment</subject><subject>Risk Factors</subject><subject>Surgery</subject><subject>Surgical Procedures, Operative - adverse effects</subject><subject>Surgical Procedures, Operative - mortality</subject><subject>Surgical Procedures, Operative - statistics & numerical data</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>United States - epidemiology</subject><subject>Young Adult</subject><issn>0039-6060</issn><issn>1532-7361</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ksGKFDEQhoMo7rj6Ah4kF_HUYyXZTndEBBlcFRYU1HPIJJUlY3dnTNIL_fammXEFD14SSL6qP_koQp4z2DJg8vVhm-d0u-VQD6DdAqgHZMNawZtOSPaQbACEaiRIuCBPcj5AJa5Y_5hccJBCdLzbkGEXx6NJIceJRk8FNM4sNM7FxhEzNb5gojhiusXJLrSumMxA12BMCz2maNHNCfMb-jUWnEqotz4mWkwlCjoaxgrd1RZTeUoeeTNkfHbeL8mP6w_fd5-amy8fP-_e3zS2BVka3smW9Z3qbK8c9sCvBHrFnDQAzCsuPW8r2HuUYPlectkrcMLtBQJzvRSX5NWpb03-NWMuegzZ4jCYCeOcdSeEUrwXXSX5ibQp5pzQ62MKo0mLZqBXyfqg17_qVbKGVleFtejFuf28H9Hdl_yxWoGXZ8BkawafzGRD_ssJkFKolXt74rDKuAuYdLahekYXEtqiXQz_f8e7f8rtEKZQE3_igvkQ5zRVzZrpzDXob-s4rNPA6iBwqbj4DeqhsAI</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Ingraham, Angela M., MD</creator><creator>Cohen, Mark E., PhD</creator><creator>Bilimoria, Karl Y., MD, MS</creator><creator>Raval, Mehul V., MD</creator><creator>Ko, Clifford Y., MD, MS, MSHS</creator><creator>Nathens, Avery B., MD, PhD</creator><creator>Hall, Bruce L., MD, PhD, MBA</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100801</creationdate><title>Comparison of 30-day outcomes after emergency general surgery procedures: Potential for targeted improvement</title><author>Ingraham, Angela M., MD ; Cohen, Mark E., PhD ; Bilimoria, Karl Y., MD, MS ; Raval, Mehul V., MD ; Ko, Clifford Y., MD, MS, MSHS ; Nathens, Avery B., MD, PhD ; Hall, Bruce L., MD, PhD, MBA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c506t-276518797c89de80243ef91d6a001f926f255068fe60c2b626890d3db3e01d863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Appendectomy - adverse effects</topic><topic>Appendectomy - mortality</topic><topic>Appendectomy - statistics & numerical data</topic><topic>Biological and medical sciences</topic><topic>Cholecystectomy - adverse effects</topic><topic>Cholecystectomy - mortality</topic><topic>Cholecystectomy - statistics & numerical data</topic><topic>Databases, Factual</topic><topic>Digestive System Surgical Procedures - adverse effects</topic><topic>Digestive System Surgical Procedures - mortality</topic><topic>Digestive System Surgical Procedures - statistics & numerical data</topic><topic>Emergency Service, Hospital - statistics & numerical data</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - mortality</topic><topic>Postoperative Complications - prevention & control</topic><topic>Risk Adjustment</topic><topic>Risk Factors</topic><topic>Surgery</topic><topic>Surgical Procedures, Operative - adverse effects</topic><topic>Surgical Procedures, Operative - mortality</topic><topic>Surgical Procedures, Operative - statistics & numerical data</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>United States - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ingraham, Angela M., MD</creatorcontrib><creatorcontrib>Cohen, Mark E., PhD</creatorcontrib><creatorcontrib>Bilimoria, Karl Y., MD, MS</creatorcontrib><creatorcontrib>Raval, Mehul V., MD</creatorcontrib><creatorcontrib>Ko, Clifford Y., MD, MS, MSHS</creatorcontrib><creatorcontrib>Nathens, Avery B., MD, PhD</creatorcontrib><creatorcontrib>Hall, Bruce L., MD, PhD, MBA</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ingraham, Angela M., MD</au><au>Cohen, Mark E., PhD</au><au>Bilimoria, Karl Y., MD, MS</au><au>Raval, Mehul V., MD</au><au>Ko, Clifford Y., MD, MS, MSHS</au><au>Nathens, Avery B., MD, PhD</au><au>Hall, Bruce L., MD, PhD, MBA</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of 30-day outcomes after emergency general surgery procedures: Potential for targeted improvement</atitle><jtitle>Surgery</jtitle><addtitle>Surgery</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>148</volume><issue>2</issue><spage>217</spage><epage>238</epage><pages>217-238</pages><issn>0039-6060</issn><eissn>1532-7361</eissn><coden>SURGAZ</coden><abstract>Background Patients who undergo emergency operations represent a high-risk population and have been shown to have a high risk of poor outcomes. Little is known, however, about the variability in the quality of emergency general surgical care across hospitals or within hospitals across different procedures. The objectives of this study were to identify risk factors associated with adverse events, to compare 30-day outcomes after 3 common emergency general surgery procedures within and across hospitals, and thus, to determine whether the quality of emergency surgical care is procedure-dependent or intrinsic to other aspects of the hospital environment. Methods Patients who underwent emergency appendectomy, cholecystectomy, or colorectal resection at 95 hospitals that submitted at least 20 of each procedure were identified in the 2005–2008 American College of Surgeons National Surgical Quality Improvement Project database. Outcomes of interest included 30-day overall morbidity and serious morbidity/mortality. Step-wise logistic regression generated patient-level predicted probabilities of an outcome. Based on the expected probabilities, observed to expected (O/E) ratios for each outcome, after each of the 3 procedures, were calculated for each hospital. Hospitals were divided into terciles based on O/E ratios. The agreement on hospital outcomes performance for overall morbidity and serious morbidity/mortality after appendectomy, cholecystectomy, and colorectal resection was assessed using weighted kappa statistics. Results Of the 30,788 appendectomies, 1,984 (6.44%) patients had any morbidity, and 1,140 (3.70%) patients had a serious morbidity or died. Of the 5,824 cholecystectomies, 503 (8.64%) patients had any morbidity, and 371 (6.37%) patients had a serious morbidity or died. Of the 8,990 colorectal resections, 4,202 (46.74%) patients had any morbidity, and 3,736 (41.56%) patients had a serious morbidity or died. For overall morbidity, O/E ratios for appendectomy ranged from 0.26 to 2.36; O/E ratios for cholecystectomy ranged from 0 to 3.04; O/E ratios for colorectal resection ranged from 0.45 to 1.51. For serious morbidity/mortality, O/E ratios for appendectomy ranged from 0.23 to 2.54; O/E ratios for cholecystectomy ranged from 0 to 4.28; O/E ratios for colorectal resection ranged from 0.59 to 1.75. Associations of risk-adjusted hospital outcomes based on tercile rank between procedures demonstrated slight but significant agreement for both overall morbidity (weighted kappa between 0.20 and 0.22) and serious morbidity/mortality (weighted kappa between 0.18 and 0.22). Despite this, 7 (7.4%) hospitals for overall morbidity and 9 (9.5%) hospitals for serious morbidity/mortality were rated in the highest (best) tercile for all procedures. Eight (8.4%) hospitals for overall morbidity and 8 (8.4%) hospitals for serious morbidity/mortality were rated in the lowest tercile for all procedures. Conclusion Emergency general surgery procedures, particularly colorectal resections, were associated with substantial 30-day overall morbidity and serious morbidity/mortality. Most hospitals did not have consistent risk-adjusted outcomes across all 3 procedures, but for a substantive minority of institutions (7–10%), good or bad performance was generalizable across procedures. Individual hospitals should examine their procedure-specific outcomes after emergency general surgery operations to focus quality improvement initiatives appropriately.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>20633727</pmid><doi>10.1016/j.surg.2010.05.009</doi><tpages>22</tpages></addata></record> |
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subjects | Adolescent Adult Aged Appendectomy - adverse effects Appendectomy - mortality Appendectomy - statistics & numerical data Biological and medical sciences Cholecystectomy - adverse effects Cholecystectomy - mortality Cholecystectomy - statistics & numerical data Databases, Factual Digestive System Surgical Procedures - adverse effects Digestive System Surgical Procedures - mortality Digestive System Surgical Procedures - statistics & numerical data Emergency Service, Hospital - statistics & numerical data Female General aspects Humans Male Medical sciences Middle Aged Postoperative Complications - epidemiology Postoperative Complications - mortality Postoperative Complications - prevention & control Risk Adjustment Risk Factors Surgery Surgical Procedures, Operative - adverse effects Surgical Procedures, Operative - mortality Surgical Procedures, Operative - statistics & numerical data Time Factors Treatment Outcome United States - epidemiology Young Adult |
title | Comparison of 30-day outcomes after emergency general surgery procedures: Potential for targeted improvement |
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