Pharmacokinetics and milk penetration of difloxacin after a long-acting formulation for subcutaneous administration to lactating goats

The single-dose disposition kinetics of difloxacin were determined in clinically normal lactating goats (n=6) after intravenous (IV) and subcutaneous (SC) administration and subcutaneous administration of a long-acting poloxamer 407 gel formulation (P407). Difloxacin concentrations were determined b...

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Veröffentlicht in:	Journal of dairy science 2010-07, Vol.93 (7), p.3056-3064
Hauptverfasser:	Marín, P., Escudero, E., Fernández-Varón, E., Ramírez, M.J., Cárceles, C.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal productions Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - analysis Anti-Bacterial Agents - pharmacokinetics antibiotics Biological and medical sciences Ciprofloxacin - administration & dosage Ciprofloxacin - analogs & derivatives Ciprofloxacin - analysis Ciprofloxacin - pharmacokinetics dairy animals difloxacin drug formulations Female Food industries Fundamental and applied biological sciences. Psychology goat milk Goats Infusions, Intravenous Infusions, Subcutaneous lactating goat lactation long-acting drug formulations long-acting formulation mastitis Microbial Sensitivity Tests Milk - chemistry Milk - microbiology milk analysis Milk and cheese industries. Ice creams milk composition nannygoats pharmacokinetics Spain Staphylococcus aureus Staphylococcus aureus - drug effects subcutaneous injection Terrestrial animal productions Vertebrates
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