Matrix metalloproteinase-1 expression can be upregulated through mitogen-activated protein kinase pathway under the influence of human epidermal growth factor receptor 2 synergized with estrogen receptor

In our previous work, Ets-1 upregulates human epidermal growth factor receptor 2 (HER2) induced matrix metalloproteinase 1 (MMP-1) expression. Based on the above knowledge and result, we hypothesized that estrogen receptor (ER) and its signaling pathway may affect MMP-1 expression under the influenc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular cancer research 2010-07, Vol.8 (7), p.1037-1047
Hauptverfasser:	Jung, Hae Hyun, Park, Yeon Hee, Jun, Hyun Jung, Kong, Jeehyun, Kim, Jeong Hoon, Kim, Jung A, Yun, Jina, Sun, Jong Mu, Won, Young Woong, Lee, Soohyeon, Kim, Seung Tae, Ahn, Jin Seok, Im, Young-Hyuck
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Humans MAP Kinase Signaling System Matrix Metalloproteinase 1 - biosynthesis Matrix Metalloproteinase 1 - genetics Matrix Metalloproteinase 1 - metabolism Mitogen-Activated Protein Kinases - genetics Mitogen-Activated Protein Kinases - metabolism Receptor, Epidermal Growth Factor - genetics Receptor, Epidermal Growth Factor - metabolism Receptor, Epidermal Growth Factor - therapeutic use Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Signal Transduction Transfection Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!