Identification and evaluation of apoptotic compounds from Garcinia paucinervis

Four new compounds, paucinervins A–D (1–4), and 15 known ones were isolated from the leaves of Garcinia paucinervis. The structures of the new compounds were elucidated by spectroscopic evidences. All of the 19 compounds were evaluated for their apoptosis-inducing effects using HeLa-C3 cells which h...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2010-07, Vol.18 (14), p.4957-4964
Hauptverfasser:	Gao, Xue-Mei, Yu, Ting, Lai, Fanny Shuk Fan, Zhou, Yan, Liu, Xin, Qiao, Chun-Feng, Song, Jing-Zheng, Chen, Shi-Lin, Luo, Kathy Qian, Xu, Hong-Xi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Apoptosis - drug effects Benzofurans - chemistry Benzofurans - isolation & purification Benzofurans - pharmacology Benzopyrans - chemistry Benzopyrans - isolation & purification Benzopyrans - pharmacology Benzoxepins - chemistry Benzoxepins - isolation & purification Benzoxepins - pharmacology Biological and medical sciences Caspase 3 - metabolism Caspase-3 Cell Survival - drug effects Garcinia - chemistry Garcinia paucinervis General pharmacology HeLa cell HeLa Cells Humans Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Leaves - chemistry Salicylates - chemistry Salicylates - isolation & purification Salicylates - pharmacology
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