Angiotensin II induces EMMPRIN expression in THP-1 macrophages via the NF-kappaB pathway

Recent studies on atherosclerosis showed that an inducer of MMPs, EMMPRIN, is highly expressed in human atheromas. This suggested the important role of EMMPRIN in the stability of atherosclerotic plaques. Angiotensin II, one of the main functional peptides in the renin-angiotensin system, is involve...

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Veröffentlicht in:	Regulatory peptides 2010-08, Vol.163 (1-3), p.88-95
Hauptverfasser:	Yang, Li-xia, Liu, Hong, Guo, Rui-wei, Ye, Jinshan, Wang, Xian-mei, Qi, Feng, Guo, Chuan-ming, Liang, Xing
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - pharmacology Basigin - genetics Basigin - metabolism Humans Macrophages - drug effects Macrophages - metabolism Matrix Metalloproteinase 9 - metabolism NF-kappa B - metabolism Tumor Cells, Cultured Up-Regulation - drug effects
Online-Zugang:	Volltext
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