Accelerated Wound Repair in ADAM-9 Knockout Animals

ADAM-9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases (ADAMs) involved in protein ectodomain shedding and cell–cell and cell–matrix interactions. Although the functions of many ADAM family members are known, the specific biological function of ADAM-9 is still unclear...

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Veröffentlicht in:	Journal of investigative dermatology 2010-08, Vol.130 (8), p.2120-2130
Hauptverfasser:	Mauch, Cornelia, Zamek, Jan, Abety, Anna N., Grimberg, Gundula, Fox, Jay W., Zigrino, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins - genetics ADAM Proteins - metabolism Animals Autoantigens - metabolism Biological and medical sciences Cell Division - physiology Cell Movement - physiology Cells, Cultured Chronic Disease Collagen Type XVII Dermatology Epidermal Cells Gene Expression - physiology Granulation Tissue - physiology Humans Keratinocytes - cytology Keratinocytes - physiology Medical sciences Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mice, Inbred C57BL Mice, Knockout Non-Fibrillar Collagens - metabolism RNA, Messenger - metabolism Skin - injuries Skin Ulcer - pathology Skin Ulcer - physiopathology Wound Healing - physiology
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