Antineutrophil cytoplasmic antibodies: A still-growing class of autoantibodies in inflammatory disorders
Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease fr...
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Veröffentlicht in: | The American Journal of Medicine 1992-12, Vol.93 (6), p.675-682 |
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Sprache: | eng |
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