174 G>C Polymorphism of Interleukin 6 Gene Promoter Affects Interleukin 6 Serum Level in Patients with Colorectal Cancer

Purpose: Experimental data suggest that interleukin 6 (IL-6) plays an important role in the development and progression of metastasis from colorectal cancer (CRC), and − 174 G > C polymorphism has been identified recently in the IL - 6 gene promoter. Therefore, the aim of the present study was to...

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Veröffentlicht in:	Clinical cancer research 2003-06, Vol.9 (6), p.2173-2176
Hauptverfasser:	BELLUCO, Claudio, OLIVIERI, Fabiola, BONAFE, Massimiliano, GIOVAGNETTI, Simona, MAMMANO, Enzo, SCALERTA, Romano, AMBROSI, Alessandro, FRANCESCHI, Claudio, NITTI, Donato, LISE, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Colorectal Neoplasms - blood Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Female Gastroenterology. Liver. Pancreas. Abdomen Humans Interleukin-6 - blood Interleukin-6 - genetics Male Medical sciences Middle Aged Polymorphism, Genetic Promoter Regions, Genetic Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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