[11C]Mirtazapine binding in depressed antidepressant nonresponders studied by PET neuroimaging

Rationale Lack of benefit from antidepressant drug therapy is a major source of human suffering, affecting at least 25% of people with major depressive disorder. We want to know whether nonresponse to antidepressants can be linked to aberrant neuroreceptor binding. Objective This study aims to asses...

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