Development of a novel expression, ZI MAX/K ZI, for determination of the counter-anion effect on the antimicrobial activity of tetrabutylammonium salts

Due to the increasing number of strains of drug-resistant bacteria, the development of new antibiotics has become increasingly important. The antibacterial properties of quaternary amines and their derivatives on both Gram-positive and Gram-negative bacteria are well known. However, an encompassing...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2009-09, Vol.19 (17), p.4984-4987
Hauptverfasser:	Ingalsbe, Michelle L., Denis, Jeffrey D.St, McGahan, Megan E., Steiner, Walter W., Priefer, Ronny
Format:	Artikel
Sprache:	eng
Schlagworte:	Anions - chemistry Anions - pharmacology Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antimicrobial Counter anion Disk Diffusion Antimicrobial Tests Quaternary Ammonium Compounds - chemistry Quaternary Ammonium Compounds - pharmacology Quaternary ammonium salts Structure-Activity Relationship Tetrabutylammonium ZI MAX/K ZI
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