Neuronal and intestinal protein kinase d isoforms mediate Na+ (salt taste)-induced learning

Ubiquitously expressed protein kinase D (PKD) isoforms are poised to disseminate signals carried by diacylglycerol (DAG). However, the in vivo regulation and functions of PKDs are poorly understood. We show that the Caenorhabditis elegans gene, dkf-2, encodes not just DKF-2A, but also a second previ...

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Veröffentlicht in:	Science signaling 2009-08, Vol.2 (83), p.ra42-ra42
Hauptverfasser:	Fu, Ya, Ren, Min, Feng, Hui, Chen, Lu, Altun, Zeynep F, Rubin, Charles S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - genetics Caenorhabditis elegans Proteins - metabolism Caenorhabditis elegans Proteins - physiology Intestines - enzymology Learning - drug effects Learning - physiology Lipase - metabolism Lipase - physiology Neurons - enzymology Protein Isoforms Protein Kinase C - metabolism Protein Kinase C - physiology Protein-Tyrosine Kinases - metabolism Protein-Tyrosine Kinases - physiology Saccharomyces cerevisiae Proteins Sodium, Dietary - pharmacology Taste - physiology
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