Psychotropic drugs and the involvement of the Akt/GSK3 signalling pathway in mental illnesses

Mental illnesses such as bipolar disorders, ADHD, depression and schizophrenia are a major public health concern worldwide. While several pharmacological agents acting on monoamine neurotransmission are used for the management of these disorders, the ultimate molecular mechanisms responsible for the...

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Veröffentlicht in:	M.S. Médecine sciences 2010-06, Vol.26 (6-7), p.647-651
Hauptverfasser:	Del'Guidice, Thomas, Beaulieu, Jean-Martin
Format:	Artikel
Sprache:	fre
Schlagworte:	Antipsychotic Agents - pharmacology Antipsychotic Agents - therapeutic use Dopamine - pharmacology Dopamine - therapeutic use Glycogen Synthase Kinase 3 - drug effects Glycogen Synthase Kinase 3 - physiology Humans Mental Disorders - drug therapy Mental Disorders - physiopathology Proto-Oncogene Proteins c-akt - drug effects Proto-Oncogene Proteins c-akt - physiology Psychotropic Drugs - pharmacology Psychotropic Drugs - therapeutic use Serotonin - pharmacology Serotonin - therapeutic use Signal Transduction - drug effects Signal Transduction - physiology
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