Endogenous protease inhibitor uptake within the graft during reperfusion in human liver transplantation

Background In experimental liver transplantation, endogenous protease inhibitors alleviate ischemia–reperfusion (I/R) injury by inhibiting proteolysis and by direct anti-inflammatory actions. We described the kinetics of endogenous protease inhibitors and explored their anti-inflammatory potential d...

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Veröffentlicht in:	Journal of hepato-biliary-pancreatic sciences 2010-03, Vol.17 (2), p.158-165
Hauptverfasser:	Ilmakunnas, Minna, Höckerstedt, Krister, Mäkisalo, Heikki, Siitonen, Sanna, Repo, Heikki, Pesonen, Eero J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adult CD11 Antigens - biosynthesis Disease Progression Enzyme-Linked Immunosorbent Assay Enzymes Female Flow Cytometry Follow-Up Studies Gastroenterology Graft Rejection - enzymology Graft Rejection - pathology Hepatology HIV Human immunodeficiency virus Humans Intraoperative Period L-Selectin - biosynthesis Leukocyte Count Liver Transplantation - physiology Male Medicine Medicine & Public Health Middle Aged monocyte Monocytes - metabolism neutrophil Neutrophils - metabolism Original Article Peptide Hydrolases - blood Prognosis Protease inhibitors Protease Inhibitors - blood reperfusion Reperfusion Injury - enzymology Secretory Leukocyte Peptidase Inhibitor - blood SLPI Surgical Oncology TIMP‐1 Tissue Inhibitor of Metalloproteinase-1 - blood Transplants & implants Young Adult
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