Differential regulation and roles of urocortins in human adrenal H295R cells

Three urocortins (Ucns) are known as members of the corticotropin-releasing factor (CRF) family of peptides and serve as natural ligands for CRF receptors. Ucn1 and Ucn3 exhibit potent effects on the adrenal system via the CRF receptors. This study aimed to explore the regulation and roles of Ucns i...

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Veröffentlicht in:	Regulatory peptides 2010-06, Vol.162 (1), p.18-25
Hauptverfasser:	Kageyama, Kazunori, Hanada, Komaki, Suda, Toshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal gland Adrenal Glands - cytology Adrenal Glands - metabolism Aldosterone Base Sequence Biological and medical sciences Cell Line, Tumor Corticotropin-releasing factor Cortisol DNA Primers Fundamental and applied biological sciences. Psychology Humans Receptors, Corticotropin-Releasing Hormone - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Urocortin Urocortins - genetics Urocortins - physiology Vertebrates: endocrinology
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