Clinical Significance of the Upregulated Osteopontin mRNA Expression in Human Colorectal Cancer

Objective Osteopontin (OPN) is a phosphorylated glycoprotein which is associated with tumor progression, development, and metastasis. Recently, it has been reported that OPN is highly upregulated in a variety of human malignancies. The aim of this study is to investigate the clinical significance of...

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Veröffentlicht in:	Journal of gastrointestinal surgery 2010, Vol.14 (1), p.74-81
Hauptverfasser:	Likui, Wang, Hong, Wang, Shuwen, Zhang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - metabolism Blotting, Western Cell Line Cell Line, Tumor Clinical significance Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - mortality Disease-Free Survival Female Gastroenterology Gene Expression Humans Intestinal Mucosa - cytology Male Medical prognosis Medicine Medicine & Public Health Metastasis Middle Aged Original Article Osteopontin - genetics Osteopontin - metabolism Polymerase chain reaction Prognosis Proteins Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Surgery Survival Rate Up-Regulation
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