Disseminated Trichosporon spp infection in preterm newborns: a case report
To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less t...
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Veröffentlicht in: | Jornal de pediatria 2009-09, Vol.85 (5), p.459-461 |
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creator | Pereira, Denise N Nader, Silvana S Nader, Paulo Martins, Patrícia G Furlan, Silvana P Hentges, Cláudia R |
description | To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less than 1,000 g at birth. Infection with Trichosporon asahii is rare and often fatal in this group of patients.
A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns.
The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly. |
doi_str_mv | 10.2223/JPED.1923 |
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A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns.
The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly.</description><identifier>ISSN: 0021-7557</identifier><identifier>EISSN: 1678-4782</identifier><identifier>DOI: 10.2223/JPED.1923</identifier><identifier>PMID: 19830348</identifier><language>eng</language><publisher>Brazil</publisher><subject>Fatal Outcome ; Humans ; Infant, Newborn ; Infant, Premature - blood ; Male ; Mycoses - microbiology ; Trichosporon - isolation & purification</subject><ispartof>Jornal de pediatria, 2009-09, Vol.85 (5), p.459-461</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c284t-b44f7f81f6e6bc8e22d6d779a48dd3d051c161699be414417672f595a6e99ec63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19830348$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pereira, Denise N</creatorcontrib><creatorcontrib>Nader, Silvana S</creatorcontrib><creatorcontrib>Nader, Paulo</creatorcontrib><creatorcontrib>Martins, Patrícia G</creatorcontrib><creatorcontrib>Furlan, Silvana P</creatorcontrib><creatorcontrib>Hentges, Cláudia R</creatorcontrib><title>Disseminated Trichosporon spp infection in preterm newborns: a case report</title><title>Jornal de pediatria</title><addtitle>J Pediatr (Rio J)</addtitle><description>To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less than 1,000 g at birth. Infection with Trichosporon asahii is rare and often fatal in this group of patients.
A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns.
The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly.</description><subject>Fatal Outcome</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature - blood</subject><subject>Male</subject><subject>Mycoses - microbiology</subject><subject>Trichosporon - isolation & purification</subject><issn>0021-7557</issn><issn>1678-4782</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLw0AYRQdRbK0u_AMyO3GROu-HO2nroxR0UddhMvmCI83DmQTx35vSgqvLhXPv4iB0TcmcMcbv1--r5Zxaxk_QlCptMqENO0VTQhjNtJR6gi5S-iJEKqvoOZpQazjhwkzRehlSgjo0rocSb2Pwn23q2tg2OHUdDk0Fvg9jCw3uIvQQa9zAT9HGJj1gh71LgCOMi_4SnVVul-DqmDP08bTaLl6yzdvz6-Jxk3lmRJ8VQlS6MrRSoApvgLFSlVpbJ0xZ8pJI6qmiytoCBBWCaqVZJa10CqwFr_gM3R5-u9h-D5D6vA7Jw27nGmiHlGvOrRSayZG8O5A-tilFqPIuhtrF35ySfG8u35vL9-ZG9ub4OhQ1lP_kURX_A9JOaK8</recordid><startdate>20090901</startdate><enddate>20090901</enddate><creator>Pereira, Denise N</creator><creator>Nader, Silvana S</creator><creator>Nader, Paulo</creator><creator>Martins, Patrícia G</creator><creator>Furlan, Silvana P</creator><creator>Hentges, Cláudia R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090901</creationdate><title>Disseminated Trichosporon spp infection in preterm newborns: a case report</title><author>Pereira, Denise N ; Nader, Silvana S ; Nader, Paulo ; Martins, Patrícia G ; Furlan, Silvana P ; Hentges, Cláudia R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c284t-b44f7f81f6e6bc8e22d6d779a48dd3d051c161699be414417672f595a6e99ec63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Fatal Outcome</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature - blood</topic><topic>Male</topic><topic>Mycoses - microbiology</topic><topic>Trichosporon - isolation & purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pereira, Denise N</creatorcontrib><creatorcontrib>Nader, Silvana S</creatorcontrib><creatorcontrib>Nader, Paulo</creatorcontrib><creatorcontrib>Martins, Patrícia G</creatorcontrib><creatorcontrib>Furlan, Silvana P</creatorcontrib><creatorcontrib>Hentges, Cláudia R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Jornal de pediatria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pereira, Denise N</au><au>Nader, Silvana S</au><au>Nader, Paulo</au><au>Martins, Patrícia G</au><au>Furlan, Silvana P</au><au>Hentges, Cláudia R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disseminated Trichosporon spp infection in preterm newborns: a case report</atitle><jtitle>Jornal de pediatria</jtitle><addtitle>J Pediatr (Rio J)</addtitle><date>2009-09-01</date><risdate>2009</risdate><volume>85</volume><issue>5</issue><spage>459</spage><epage>461</epage><pages>459-461</pages><issn>0021-7557</issn><eissn>1678-4782</eissn><abstract>To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less than 1,000 g at birth. Infection with Trichosporon asahii is rare and often fatal in this group of patients.
A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns.
The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly.</abstract><cop>Brazil</cop><pmid>19830348</pmid><doi>10.2223/JPED.1923</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Fatal Outcome Humans Infant, Newborn Infant, Premature - blood Male Mycoses - microbiology Trichosporon - isolation & purification |
title | Disseminated Trichosporon spp infection in preterm newborns: a case report |
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