Disseminated Trichosporon spp infection in preterm newborns: a case report

To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less t...

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Veröffentlicht in:Jornal de pediatria 2009-09, Vol.85 (5), p.459-461
Hauptverfasser: Pereira, Denise N, Nader, Silvana S, Nader, Paulo, Martins, Patrícia G, Furlan, Silvana P, Hentges, Cláudia R
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container_end_page 461
container_issue 5
container_start_page 459
container_title Jornal de pediatria
container_volume 85
creator Pereira, Denise N
Nader, Silvana S
Nader, Paulo
Martins, Patrícia G
Furlan, Silvana P
Hentges, Cláudia R
description To report the first case of disseminated Trichosporon spp infection in a newborn infant in Brazil, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn infants weighing less than 1,000 g at birth. Infection with Trichosporon asahii is rare and often fatal in this group of patients. A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns. The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly.
doi_str_mv 10.2223/JPED.1923
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subjects Fatal Outcome
Humans
Infant, Newborn
Infant, Premature - blood
Male
Mycoses - microbiology
Trichosporon - isolation & purification
title Disseminated Trichosporon spp infection in preterm newborns: a case report
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