Characterization of a fibronectin-binding protein from Lactobacillus casei BL23

To characterize the functionality of the Lactobacillus casei BL23 fbpA gene encoding a putative fibronectin-binding protein. Adhesion tests showed that L. casei BL23 binds immobilized and soluble fibronectin in a protease-sensitive manner. A mutant with inactivated fbpA showed a decrease in binding...

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Veröffentlicht in:	Journal of applied microbiology 2010-03, Vol.108 (3), p.1050-1059
Hauptverfasser:	Muñoz-Provencio, D, Pérez-Martínez, G, Monedero, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - genetics Adhesins, Bacterial - metabolism Adhesion Adhesion tests Animals Antibodies Bacterial Adhesion Biological and medical sciences Caco-2 Cells Cell adhesion Cell lines Cell Membrane - metabolism Cell surface extracellular matrix Female Fibronectin Fibronectins - metabolism Fundamental and applied biological sciences. Psychology Genes, Bacterial HT29 Cells Humans Hydrophobic and Hydrophilic Interactions Hydrophobicity Lactobacilli Lactobacillus casei Lactobacillus casei - genetics Lactobacillus casei - metabolism Lithium chloride Mice Mice, Inbred BALB C Microbiology Microorganisms Mutation Probiotics Protease Proteinase Proteins
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