Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro

Nonalcoholic steatohepatitis with fibrosis is a more severe form of nonalcoholic fatty liver disease, one of the most common liver diseases. We have previously shown that peroxisome proliferator-activated receptors gamma (PPARγ) ligand, rosiglitazone, prevented the development of the methionine chol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The international journal of biochemistry & cell biology 2010-06, Vol.42 (6), p.948-957
Hauptverfasser:	Yu, Jun, Zhang, Sui, Chu, Eagle S.H., Go, Minnie Y.Y., Lau, Rebecca H.Y., Zhao, Junhong, Wu, Chung-Wah, Tong, Lixin, Zhao, Jingmin, Poon, Terence C.W., Sung, Joseph J.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae Animals Apoptosis - genetics Cell Proliferation Cloning, Molecular Connective Tissue Growth Factor - genetics Connective Tissue Growth Factor - metabolism Deficiency Diseases - genetics Deficiency Diseases - metabolism Deficiency Diseases - pathology Deficiency Diseases - therapy Disease Models, Animal Fatty Liver - genetics Fatty Liver - metabolism Fatty Liver - pathology Fatty Liver - therapy Fibrosis Gene modulation Genetic deficiency mouse model Genetic Therapy Genetic Vectors Hepatic stellat cell Hepatic Stellate Cells - metabolism Hepatic Stellate Cells - pathology Liver Cirrhosis Male Mice Mice, Inbred C57BL Nutritional steatohepatitis PPAR gamma - genetics PPAR gamma - metabolism PPARγ
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!