An Iron-Based Cytosolic Catalase and Superoxide Dismutase Mimic Complex

The development of metallodrugs with antioxidant activities is of importance as a way to protect organisms exposed to stressful conditions. Although iron chemistry in the presence of H2O2 is usually associated with pro-oxidant activity, mainly via the Fenton reaction, we found that the mononuclear c...

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Veröffentlicht in:	Inorganic chemistry 2010-02, Vol.49 (4), p.1274-1276
Hauptverfasser:	Horn, Adolfo, Parrilha, Gabrieli L, Melo, Karen V, Fernandes, Christiane, Horner, Manfredo, Visentin, Lorenzo do C, Santos, Jullyane A. S, Santos, Monique S, Eleutherio, Elis C.A, Pereira, Marcos D
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - pharmacology Catalase - chemistry Catalase - metabolism Cytosol - enzymology Hydrogen Peroxide - metabolism Iron - chemistry Iron - metabolism Ligands Molecular Structure Oxidative Stress Protein Binding Reactive Oxygen Species - pharmacology Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae Proteins - metabolism Superoxide Dismutase - chemistry Superoxide Dismutase - metabolism
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