Effects of angiotensin II type 1 receptor antagonist on electrical and structural remodeling in atrial fibrillation

The purpose of the present study was to evaluate the effect of angiotensin II type 1 receptor (AT1R) antagonist on chronic structural remodeling in atrial fibrillation (AF). We previously reported that an AT1R antagonist, candesartan, prevents acute electrical remodeling in a rapid pacing model. How...

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Veröffentlicht in:	Journal of the American College of Cardiology 2003-06, Vol.41 (12), p.2197-2204
Hauptverfasser:	Kumagai, Koichiro, Nakashima, Hideko, Urata, Hidenori, Gondo, Naoki, Arakawa, Kikuo, Saku, Keijiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Receptor Antagonists Animals Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Atrial Fibrillation - drug therapy Atrial Fibrillation - etiology Atrial Fibrillation - physiopathology Benzimidazoles - pharmacology Benzimidazoles - therapeutic use Cardiac arrhythmia Cardiac Pacing, Artificial - adverse effects Cardiology Chronic Disease Colorectal cancer Disease Models, Animal Dogs Drug therapy Electrophysiology Female Heart Conduction System - drug effects Heart Conduction System - pathology Heart Conduction System - physiopathology Hemodynamics - drug effects Hemodynamics - physiology Male Postoperative period Random Allocation Receptors, Angiotensin - therapeutic use Tetrazoles - pharmacology Tetrazoles - therapeutic use Time Factors Ventricular Remodeling - drug effects Ventricular Remodeling - physiology
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