Identification of pancreatic juice proteins as biomarkers of pancreatic cancer

Pancreatic juice is a potential source of proteins associated with pancreatic cancer (PC) due to the proximity of ducts to tumor tissue. Therefore, screening of proteins in pancreatic juice from PC patients may identify new PC biomarkers. We analyzed pancreatic juice from patients with pancreatic di...

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Veröffentlicht in:	Oncology reports 2010-06, Vol.23 (6), p.1683-1692
Hauptverfasser:	Gao, Jun, Zhu, Feng, Lv, Shunli, Li, Zhaoshen, Ling, Zhang, Gong, Yanfang, Jie, Chen, Ma, Lie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - pathology Choledocholithiasis - genetics Choledocholithiasis - metabolism Choledocholithiasis - pathology Chymotrypsin - genetics Chymotrypsin - metabolism DNA Methylation Electrophoresis, Gel, Two-Dimensional Female Gastroenterology. Liver. Pancreas. Abdomen Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Nuclear Proteins - genetics Nuclear Proteins - metabolism Pancreas - metabolism Pancreas - pathology Pancreatic Elastase - genetics Pancreatic Elastase - metabolism Pancreatic Juice - metabolism Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Pancreatitis, Chronic - genetics Pancreatitis, Chronic - metabolism Pancreatitis, Chronic - pathology Prognosis Promoter Regions, Genetic Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Trypsin - genetics Trypsin - metabolism Trypsinogen - genetics Trypsinogen - metabolism Tumor Cells, Cultured Tumors
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