A hypertonicity-activated nonselective conductance in single proximal tubule cells isolated from mouse kidney

The whole-cell patch-clamp technique was used to examine nonselective conductances in single proximal tubule cells isolated from mouse kidney. Single cells were isolated in either the presence or absence of a cocktail designed to stimulate cAMP. Patches were obtained with Na+ Ringer in the bath and...

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Veröffentlicht in:	The Journal of membrane biology 2003-04, Vol.192 (3), p.191-201
Hauptverfasser:	Balloch, K J D, Hartley, J A, Millar, I D, Kibble, J D, Robson, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals Cell Size - physiology Cells, Cultured Cyclic AMP - metabolism Electric Conductivity Hypertonic Solutions Ion Channel Gating - drug effects Ion Channel Gating - physiology Ion Channels - physiology Kidney Tubules, Proximal - cytology Kidney Tubules, Proximal - drug effects Kidney Tubules, Proximal - physiology Mechanotransduction, Cellular - physiology Membrane Potentials - drug effects Membrane Potentials - physiology Mice Mice, Inbred C57BL Osmotic Pressure
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