Therapeutic Hotline: Facial skin rejuvenation in a patient treated with photodynamic therapy for actinic keratosis
ABSTRACT The aim of the most used treatments of actinic keratoses (AKs) is to avoid the conversion into invasive squamous cell carcinoma through the destruction of the lesion; a lot of therapeutic modalities (imiquimod, 5‐fluorouracil, electrosurgery with curettage, cryosurgery) are effective and sa...
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creator | Bruscino, Nicola Rossi, Riccardo Dindelli, Margherita Ghersetich, Ilaria Lotti, Torello |
description | ABSTRACT
The aim of the most used treatments of actinic keratoses (AKs) is to avoid the conversion into invasive squamous cell carcinoma through the destruction of the lesion; a lot of therapeutic modalities (imiquimod, 5‐fluorouracil, electrosurgery with curettage, cryosurgery) are effective and safe in this field, but not many can do it with excellent cosmetic results like treatment with photodynamic therapy (PDT). We have treated with this technique an old patient, whose AK was resistant to other treatments; the most interesting feature of our case comes from the esthetic effects of the PDT employing a methyl‐ester of 5‐aminolevulinic acid as topical photosensitizer. This kind of therapy has removed not only the lesion but also the photoaging manifestations like the wrinkles and the ugly lines, leaving a smooth skin, as we have proved with 3D‐profilometry technique. |
doi_str_mv | 10.1111/j.1529-8019.2009.01294.x |
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The aim of the most used treatments of actinic keratoses (AKs) is to avoid the conversion into invasive squamous cell carcinoma through the destruction of the lesion; a lot of therapeutic modalities (imiquimod, 5‐fluorouracil, electrosurgery with curettage, cryosurgery) are effective and safe in this field, but not many can do it with excellent cosmetic results like treatment with photodynamic therapy (PDT). We have treated with this technique an old patient, whose AK was resistant to other treatments; the most interesting feature of our case comes from the esthetic effects of the PDT employing a methyl‐ester of 5‐aminolevulinic acid as topical photosensitizer. This kind of therapy has removed not only the lesion but also the photoaging manifestations like the wrinkles and the ugly lines, leaving a smooth skin, as we have proved with 3D‐profilometry technique.</description><identifier>ISSN: 1396-0296</identifier><identifier>EISSN: 1529-8019</identifier><identifier>DOI: 10.1111/j.1529-8019.2009.01294.x</identifier><identifier>PMID: 20136912</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>3D-profilometry ; actinic keratoses ; Aged, 80 and over ; Aminolevulinic Acid - therapeutic use ; Carcinoma, Squamous Cell - prevention & control ; facial skin rejuvenation ; Female ; Humans ; Keratosis, Actinic - drug therapy ; Keratosis, Actinic - radiotherapy ; Photochemotherapy - methods ; photodynamic therapy ; Photosensitizing Agents - therapeutic use ; Rejuvenation ; Skin Aging - radiation effects ; Skin Neoplasms - prevention & control</subject><ispartof>Dermatologic therapy, 2010-01, Vol.23 (1), p.86-89</ispartof><rights>2010 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4564-b38446d4b11fc14fbb63a3f6d65f1e37189ec15bc03edf8dc7d89da1b065e2d73</citedby><cites>FETCH-LOGICAL-c4564-b38446d4b11fc14fbb63a3f6d65f1e37189ec15bc03edf8dc7d89da1b065e2d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1529-8019.2009.01294.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1529-8019.2009.01294.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20136912$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bruscino, Nicola</creatorcontrib><creatorcontrib>Rossi, Riccardo</creatorcontrib><creatorcontrib>Dindelli, Margherita</creatorcontrib><creatorcontrib>Ghersetich, Ilaria</creatorcontrib><creatorcontrib>Lotti, Torello</creatorcontrib><title>Therapeutic Hotline: Facial skin rejuvenation in a patient treated with photodynamic therapy for actinic keratosis</title><title>Dermatologic therapy</title><addtitle>Dermatol Ther</addtitle><description>ABSTRACT
The aim of the most used treatments of actinic keratoses (AKs) is to avoid the conversion into invasive squamous cell carcinoma through the destruction of the lesion; a lot of therapeutic modalities (imiquimod, 5‐fluorouracil, electrosurgery with curettage, cryosurgery) are effective and safe in this field, but not many can do it with excellent cosmetic results like treatment with photodynamic therapy (PDT). We have treated with this technique an old patient, whose AK was resistant to other treatments; the most interesting feature of our case comes from the esthetic effects of the PDT employing a methyl‐ester of 5‐aminolevulinic acid as topical photosensitizer. This kind of therapy has removed not only the lesion but also the photoaging manifestations like the wrinkles and the ugly lines, leaving a smooth skin, as we have proved with 3D‐profilometry technique.</description><subject>3D-profilometry</subject><subject>actinic keratoses</subject><subject>Aged, 80 and over</subject><subject>Aminolevulinic Acid - therapeutic use</subject><subject>Carcinoma, Squamous Cell - prevention & control</subject><subject>facial skin rejuvenation</subject><subject>Female</subject><subject>Humans</subject><subject>Keratosis, Actinic - drug therapy</subject><subject>Keratosis, Actinic - radiotherapy</subject><subject>Photochemotherapy - methods</subject><subject>photodynamic therapy</subject><subject>Photosensitizing Agents - therapeutic use</subject><subject>Rejuvenation</subject><subject>Skin Aging - radiation effects</subject><subject>Skin Neoplasms - prevention & control</subject><issn>1396-0296</issn><issn>1529-8019</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEFv1DAUhC0EomXhLyDfOCXYsePESBxQaRtQRS9bcbQc-0Xr3WwSbIfu_vs63bJnfPG855mx9CGEKclpOp-3OS0LmdWEyrwgROaEFpLnh1fo8vzwOmkmRUYKKS7QuxC2ZHEx-hZdFIQyIWlxifx6A15PMEdncDPG3g3wBd9o43SPw84N2MN2_guDjm4ccJo1npKGIeLoQUew-NHFDZ42YxztcdD7VBSfS4-4Gz3WJroh7XZpFcfgwnv0ptN9gA8v9wo93Fyvr5rs7v72x9W3u8zwUvCsZTXnwvKW0s5Q3rWtYJp1woqyo8AqWkswtGwNYWC72prK1tJq2hJRQmErtkKfTr2TH__MEKLau2Cg7_UA4xxUxZgsqjKhWKH65DR-DMFDpybv9tofFSVqAa62auGqFq5qAa6egatDin58-WRu92DPwX-Ek-HryfDoejj-d7H6vm4WlfLZKe9ChMM5r_1OiYpVpfr961aRZt385A1XnD0B9bOgag</recordid><startdate>201001</startdate><enddate>201001</enddate><creator>Bruscino, Nicola</creator><creator>Rossi, Riccardo</creator><creator>Dindelli, Margherita</creator><creator>Ghersetich, Ilaria</creator><creator>Lotti, Torello</creator><general>Blackwell Publishing Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201001</creationdate><title>Therapeutic Hotline: Facial skin rejuvenation in a patient treated with photodynamic therapy for actinic keratosis</title><author>Bruscino, Nicola ; Rossi, Riccardo ; Dindelli, Margherita ; Ghersetich, Ilaria ; Lotti, Torello</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4564-b38446d4b11fc14fbb63a3f6d65f1e37189ec15bc03edf8dc7d89da1b065e2d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>3D-profilometry</topic><topic>actinic keratoses</topic><topic>Aged, 80 and over</topic><topic>Aminolevulinic Acid - therapeutic use</topic><topic>Carcinoma, Squamous Cell - prevention & control</topic><topic>facial skin rejuvenation</topic><topic>Female</topic><topic>Humans</topic><topic>Keratosis, Actinic - drug therapy</topic><topic>Keratosis, Actinic - radiotherapy</topic><topic>Photochemotherapy - methods</topic><topic>photodynamic therapy</topic><topic>Photosensitizing Agents - therapeutic use</topic><topic>Rejuvenation</topic><topic>Skin Aging - radiation effects</topic><topic>Skin Neoplasms - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bruscino, Nicola</creatorcontrib><creatorcontrib>Rossi, Riccardo</creatorcontrib><creatorcontrib>Dindelli, Margherita</creatorcontrib><creatorcontrib>Ghersetich, Ilaria</creatorcontrib><creatorcontrib>Lotti, Torello</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bruscino, Nicola</au><au>Rossi, Riccardo</au><au>Dindelli, Margherita</au><au>Ghersetich, Ilaria</au><au>Lotti, Torello</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Therapeutic Hotline: Facial skin rejuvenation in a patient treated with photodynamic therapy for actinic keratosis</atitle><jtitle>Dermatologic therapy</jtitle><addtitle>Dermatol Ther</addtitle><date>2010-01</date><risdate>2010</risdate><volume>23</volume><issue>1</issue><spage>86</spage><epage>89</epage><pages>86-89</pages><issn>1396-0296</issn><eissn>1529-8019</eissn><abstract>ABSTRACT
The aim of the most used treatments of actinic keratoses (AKs) is to avoid the conversion into invasive squamous cell carcinoma through the destruction of the lesion; a lot of therapeutic modalities (imiquimod, 5‐fluorouracil, electrosurgery with curettage, cryosurgery) are effective and safe in this field, but not many can do it with excellent cosmetic results like treatment with photodynamic therapy (PDT). We have treated with this technique an old patient, whose AK was resistant to other treatments; the most interesting feature of our case comes from the esthetic effects of the PDT employing a methyl‐ester of 5‐aminolevulinic acid as topical photosensitizer. This kind of therapy has removed not only the lesion but also the photoaging manifestations like the wrinkles and the ugly lines, leaving a smooth skin, as we have proved with 3D‐profilometry technique.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>20136912</pmid><doi>10.1111/j.1529-8019.2009.01294.x</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 3D-profilometry actinic keratoses Aged, 80 and over Aminolevulinic Acid - therapeutic use Carcinoma, Squamous Cell - prevention & control facial skin rejuvenation Female Humans Keratosis, Actinic - drug therapy Keratosis, Actinic - radiotherapy Photochemotherapy - methods photodynamic therapy Photosensitizing Agents - therapeutic use Rejuvenation Skin Aging - radiation effects Skin Neoplasms - prevention & control |
title | Therapeutic Hotline: Facial skin rejuvenation in a patient treated with photodynamic therapy for actinic keratosis |
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