LIGHT contributes to early but not late control of Mycobacterium tuberculosis infection

The TNF superfamily member, LIGHT, contributes to optimal T-cell activation in vitro through co-stimulation of dendritic cell cytokine production; however, its role in T-cell-mediated control of intracellular bacterial infections is unknown. Protective immunity against Listeria monocytogenes and Myc...

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Veröffentlicht in:	International immunology 2010-05, Vol.22 (5), p.353-358
Hauptverfasser:	Musicki, Korana, Briscoe, Helen, Britton, Warwick J., Saunders, Bernadette M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD8-Positive T-Lymphocytes - cytology CD8-Positive T-Lymphocytes - immunology Cell Proliferation cytokines inflammation intracellular pathogens LIGHT Listeria monocytogenes - immunology Listeria monocytogenes - isolation & purification Mice Mice, Inbred C57BL Mycobacterium Infections - immunology Mycobacterium tuberculosis - immunology Mycobacterium tuberculosis - isolation & purification T-cell co-stimulation Tumor Necrosis Factor Ligand Superfamily Member 14 - deficiency Tumor Necrosis Factor Ligand Superfamily Member 14 - immunology
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