Proteome alteration of U251 human astrocytoma cell after inhibiting retinoic acid synthesis

Retinoic acid (Ra) is crucial for the patterning and neuronal differentiation in the central nervous system (CNS). Ra deficiency in animals disrupts the motor activities and memory abilities. The molecular mechanisms underlying these behavior abnormalities remain largely unknown. In the current stud...

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Veröffentlicht in:	Molecular and cellular biochemistry 2009-03, Vol.323 (1-2), p.185-193
Hauptverfasser:	Zhang, Ming, Wan, Chunling, Ji, Baohu, Zhang, Zhao, Zhu, Hui, Tian, Nan, La, Yujuan, Huang, Ke, Jiang, Lei, He, Guang, Gao, Linhan, Zhao, Xinzhi, Shi, Yongyong, Huang, Gang, Feng, Guoyin, He, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytoma - metabolism Biochemistry Biomedical and Life Sciences Biophysics Cardiology Cell Line, Tumor - drug effects Cellular biology Central nervous system Computational Biology - methods Electrophoresis, Gel, Two-Dimensional Humans Ionization Life Sciences Mass spectrometry Medical Biochemistry Memory Mental disorders Molecular biology Molecular Sequence Data Monoterpenes - pharmacology Oncology Oxidative stress Phosphoglycerate Dehydrogenase - genetics Phosphoglycerate Dehydrogenase - metabolism Proteins Proteome - metabolism Proteomics Proteomics - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tretinoin - metabolism
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