Protein-Protein Complex Formation Affects the Ni-Fe and Fe-S Centers in the H2-Sensing Regulatory Hydrogenase from Ralstonia eutropha H16

The regulatory Ni–Fe hydrogenase (RH) from the H2‐oxidizing bacterium Ralstonia eutropha functions as an oxygen‐resistant hydrogen sensor, which is composed of the large, active‐site‐containing HoxC subunit and the small subunit HoxB carrying Fe–S clusters. In vivo, the HoxBC subunits form a dimer d...

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