Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems
The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) dendrimers are capable of supporting heavy meromyosin dependent actin motility of similar quality to that observed using nitrocellulose, and th...
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Veröffentlicht in: | Langmuir 2010-05, Vol.26 (9), p.6079-6082 |
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creator | Kolli, Madhukar B Day, B. Scott Takatsuki, Hideyo Nalabotu, Siva K Rice, Kevin M Kohama, Kazuhiro Gadde, Murali K Kakarla, Sunil K Katta, Anjaiah Blough, Eric R |
description | The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) dendrimers are capable of supporting heavy meromyosin dependent actin motility of similar quality to that observed using nitrocellulose, and that microcontact printing of PAMAM dendrimers can be exploited to produce tracks of active myosin motors leading to the restricted motion of actin filaments across a patterned surface. These data suggest that the use of dendrimer surfaces will increase the applicability of using protein biomolecular motors for nanotechnological applications. |
doi_str_mv | 10.1021/la100174h |
format | Article |
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Scott</creatorcontrib><creatorcontrib>Takatsuki, Hideyo</creatorcontrib><creatorcontrib>Nalabotu, Siva K</creatorcontrib><creatorcontrib>Rice, Kevin M</creatorcontrib><creatorcontrib>Kohama, Kazuhiro</creatorcontrib><creatorcontrib>Gadde, Murali K</creatorcontrib><creatorcontrib>Kakarla, Sunil K</creatorcontrib><creatorcontrib>Katta, Anjaiah</creatorcontrib><creatorcontrib>Blough, Eric R</creatorcontrib><title>Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems</title><title>Langmuir</title><addtitle>Langmuir</addtitle><description>The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. 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These data suggest that the use of dendrimer surfaces will increase the applicability of using protein biomolecular motors for nanotechnological applications.</description><subject>Animals</subject><subject>Cattle</subject><subject>Chemistry</subject><subject>Collodion - chemistry</subject><subject>Colloidal state and disperse state</subject><subject>Dendrimers - chemistry</subject><subject>Electricity</subject><subject>Exact sciences and technology</subject><subject>General and physical chemistry</subject><subject>Movement</subject><subject>Myosins - metabolism</subject><subject>Nanotechnology - methods</subject><subject>Surface physical chemistry</subject><subject>Surface Properties</subject><subject>Tin Compounds - chemistry</subject><issn>0743-7463</issn><issn>1520-5827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0LtOwzAUBmALgWgpDLwAyoKgQ-D4FsdjKXdVAgk6R65ji1RJXOxk6Ntj1NIuLD6S9elcfoTOMdxgIPi2VhgAC_Z1gIaYE0h5TsQhGoJgNBUsowN0EsISACRl8hgNCFDOBWND9DpZrepKq65ybeJs8u7q9bVqqtLFpzXj5N60pa8a40NinU_mwSRVm9xFrlrXuC7-faxDZ5pwio6sqoM529YRmj8-fE6f09nb08t0MksVZaxLmdGy1FZxSgEDw3ghS7Bc55ATI-JemhBKNJMZt-Uiz7gRWkhglBkuS2XoCF1t-q68--5N6IqmCtrUtWqN60MhKJWYEcyjHG-k9i4Eb2yxiqcovy4wFL_JFbvkor3Ydu0XjSl38i-qCC63QAWtautVq6uwdySTHHO-d0qHYul638Yw_hn4A7hqgHk</recordid><startdate>20100504</startdate><enddate>20100504</enddate><creator>Kolli, Madhukar B</creator><creator>Day, B. 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subjects | Animals Cattle Chemistry Collodion - chemistry Colloidal state and disperse state Dendrimers - chemistry Electricity Exact sciences and technology General and physical chemistry Movement Myosins - metabolism Nanotechnology - methods Surface physical chemistry Surface Properties Tin Compounds - chemistry |
title | Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems |
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