Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems

The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) dendrimers are capable of supporting heavy meromyosin dependent actin motility of similar quality to that observed using nitrocellulose, and th...

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Veröffentlicht in:Langmuir 2010-05, Vol.26 (9), p.6079-6082
Hauptverfasser: Kolli, Madhukar B, Day, B. Scott, Takatsuki, Hideyo, Nalabotu, Siva K, Rice, Kevin M, Kohama, Kazuhiro, Gadde, Murali K, Kakarla, Sunil K, Katta, Anjaiah, Blough, Eric R
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container_end_page 6082
container_issue 9
container_start_page 6079
container_title Langmuir
container_volume 26
creator Kolli, Madhukar B
Day, B. Scott
Takatsuki, Hideyo
Nalabotu, Siva K
Rice, Kevin M
Kohama, Kazuhiro
Gadde, Murali K
Kakarla, Sunil K
Katta, Anjaiah
Blough, Eric R
description The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) dendrimers are capable of supporting heavy meromyosin dependent actin motility of similar quality to that observed using nitrocellulose, and that microcontact printing of PAMAM dendrimers can be exploited to produce tracks of active myosin motors leading to the restricted motion of actin filaments across a patterned surface. These data suggest that the use of dendrimer surfaces will increase the applicability of using protein biomolecular motors for nanotechnological applications.
doi_str_mv 10.1021/la100174h
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subjects Animals
Cattle
Chemistry
Collodion - chemistry
Colloidal state and disperse state
Dendrimers - chemistry
Electricity
Exact sciences and technology
General and physical chemistry
Movement
Myosins - metabolism
Nanotechnology - methods
Surface physical chemistry
Surface Properties
Tin Compounds - chemistry
title Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems
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