Cytotoxic alkyl benzoquinones and alkyl phenols from Ardisia virens

Fourteen compounds ( 1– 14), together with thirty-four other known compounds, including three ( 15– 17) were isolated from Ardisia virens. Compounds 3, 10– 12, 18, 19, and 31 displayed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines in vitro. Bioassay-guided fractionation of roots...

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Veröffentlicht in:	Phytochemistry (Oxford) 2009-12, Vol.70 (17), p.2064-2071
Hauptverfasser:	Chang, Hsun-Shuo, Lin, Yi-Ju, Lee, Shiow-Ju, Yang, Cheng-Wei, Lin, Wei-Yu, Tsai, Ian-Lih, Chen, Ih-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkanes - isolation & purification Alkyl benzoquinone Alkyl phenol Alkylation anticarcinogenic activity Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use Ardisia Ardisia - chemistry Ardisia virens ardisianol ardisianone benzoquinones Benzoquinones - isolation & purification Benzoquinones - pharmacology Benzoquinones - therapeutic use Biological and medical sciences Cell Line, Tumor Chemical constitution chemical structure comudentanone Cytotoxicity Fundamental and applied biological sciences. Psychology Heptanes - isolation & purification human diseases human health Humans hydroxybenzene Inhibitory Concentration 50 medicinal plants Myrsinaceae Neoplasms - drug therapy phenols Phenols - isolation & purification Phenols - pharmacology Phenols - therapeutic use phytochemicals Phytotherapy Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant physiology and development Plant Roots Plant Stems Root spectral analysis Stem stereochemistry virenol
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