Studies of the Toxicological Potential of Capsinoids, XI: Pharmacokinetic and Tissue Distribution Study of 14C-Dihydrocapsiate and Metabolites in Rats

Pharmacokinetics of a single gavage dose of 14C-labeled dihydrocapsiate (10 mg/kg) were investigated in male rats. Maximal plasma concentration was achieved in 40 minutes and exhibited an apparent half-life of 2.4 hours. Excretion of radioactivity in the urine, feces, and expired air was 78.2%, 19.4...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of toxicology 2010-03, Vol.29 (2_suppl), p.3S-14S
Hauptverfasser:	Bernard, Bruce K., Ubukata, Kazuyuki, Mihara, Ryuichi, Sato, Yoshiaki, Nemoto, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Capsaicin - analogs & derivatives Capsaicin - pharmacokinetics Carbon Radioisotopes Chromatography, High Pressure Liquid Male Rats Tissue Distribution
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!