High phosphorus diet induces vascular calcification, a related decrease in bone mass and changes in the aortic gene expression

Abstract In chronic kidney disease, hyperphosphatemia has been associated to vascular calcifications. Moreover, the rate and progression of vascular calcification have been related with the reduction of bone mass and osteoporotic fractures, hereby suggesting a strong link between vascular calcificat...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2010-01, Vol.46 (1), p.121-128
Hauptverfasser:	Román-García, Pablo, Carrillo-López, Natalia, Fernández-Martín, José Luis, Naves-Díaz, Manuel, Ruiz-Torres, María Piedad, Cannata-Andía, Jorge B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - drug effects Aorta - metabolism Biological and medical sciences Bone and Bones - drug effects Bone and Bones - metabolism Bone and Bones - pathology Bone Density - drug effects Bone mass Calcinosis - chemically induced Calcinosis - metabolism Calcinosis - pathology Densitometry Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Gene Expression - genetics High phosphorus diet Male Oligonucleotide Array Sequence Analysis Orthopedics Phosphorus - administration & dosage Phosphorus - adverse effects Rats Rats, Wistar Vascular calcification Vascular Diseases - chemically induced Vascular Diseases - metabolism Vascular Diseases - pathology Vascular wall gene expression Vertebrates: anatomy and physiology, studies on body, several organs or systems Wnt pathway inhibitors
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