Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin
BACKGROUND Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommen...
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| Veröffentlicht in: | Dermatologic surgery 2010-04, Vol.36 (4), p.483-489 |
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| creator | BAGATIN, EDILÉIA DOS SANTOS GUADANHIM, LILIA RAMOS YARAK, SAMIRA KAMAMOTO, CRISTHINE SOUZA LEÃO DE ALMEIDA, FERNANDO AUGUSTO |
| description | BACKGROUND
Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommended 6 to 12 months from the end of oral isotretinoin treatment.
OBJECTIVE
To evaluate wound healing after localized dermabrasion in patients receiving oral isotretinoin.
MATERIALS & METHODS
Interventional, prospective study involving seven patients taking oral isotretinoin to treat acne and with atrophic acne scars on the face. Manual dermabrasion was performed on all patients in an area of approximately 1 cm2, and a 6‐month reepithelization follow‐up by clinical evaluation was conducted.
RESULTS
All patients presented normal cicatrization evolution; hypertrophic scarring or keloid as a result of localized abrasion was not observed, and atrophic acne scar revision result was excellent.
CONCLUSION
The current recommendation to wait 6 to 12 months after treatment with oral isotretinoin for acne scar revision using dermabrasion should be re‐evaluated. Abrasion of a small test area may be a useful predictor of wound healing, enabling earlier acne scar treatment using this procedure.
The authors have indicated no significant interest with commercial supporters. |
| doi_str_mv | 10.1111/j.1524-4725.2010.01474.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733898629</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733898629</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3984-de5b77992d56451a0d7a4b378320fa58ae27db949ee0628654aae9bec55171793</originalsourceid><addsrcrecordid>eNqNkD1v2zAQhomgRZ24_QsFl6KTXH6K5NAhsJM0QIAMTmbiJJ1SGvpISRm2_32k2HXXcuGB97zHw0MI5WzBx_Njs-BaqEwZoReCja-MK6MW-wtyeW58GGtm8oxpLmbkKqUNY1w4yT6R2ZixzMr8kixXGFsoIqTQd7TuI70uO6TrEmKiq20M3Qt9ighDi91Ad2H4TR8jNPQ-9UPEIXR96D6TjzU0Cb-c7jl5vr15Wv7KHh7v7pfXD1kpnVVZhbowxjlR6VxpDqwyoApprBSsBm0BhakKpxwiy4XNtQJAV2CpNTfcODkn349zX2P_Z4tp8G1IJTYNdNhvkzdSWmdzMZH2SJaxTyli7V9jaCEePGd-Mug3fhLlJ1F-MujfDfr9GP16-mRbtFidg3-VjcC3EwCphKaO0JUh_eOE0UIyOXI_j9wuNHj47wX8av08VfINVVKKug</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733898629</pqid></control><display><type>article</type><title>Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Journals@Ovid Complete</source><creator>BAGATIN, EDILÉIA ; DOS SANTOS GUADANHIM, LILIA RAMOS ; YARAK, SAMIRA ; KAMAMOTO, CRISTHINE SOUZA LEÃO ; DE ALMEIDA, FERNANDO AUGUSTO</creator><creatorcontrib>BAGATIN, EDILÉIA ; DOS SANTOS GUADANHIM, LILIA RAMOS ; YARAK, SAMIRA ; KAMAMOTO, CRISTHINE SOUZA LEÃO ; DE ALMEIDA, FERNANDO AUGUSTO</creatorcontrib><description>BACKGROUND
Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommended 6 to 12 months from the end of oral isotretinoin treatment.
OBJECTIVE
To evaluate wound healing after localized dermabrasion in patients receiving oral isotretinoin.
MATERIALS & METHODS
Interventional, prospective study involving seven patients taking oral isotretinoin to treat acne and with atrophic acne scars on the face. Manual dermabrasion was performed on all patients in an area of approximately 1 cm2, and a 6‐month reepithelization follow‐up by clinical evaluation was conducted.
RESULTS
All patients presented normal cicatrization evolution; hypertrophic scarring or keloid as a result of localized abrasion was not observed, and atrophic acne scar revision result was excellent.
CONCLUSION
The current recommendation to wait 6 to 12 months after treatment with oral isotretinoin for acne scar revision using dermabrasion should be re‐evaluated. Abrasion of a small test area may be a useful predictor of wound healing, enabling earlier acne scar treatment using this procedure.
The authors have indicated no significant interest with commercial supporters.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1111/j.1524-4725.2010.01474.x</identifier><identifier>PMID: 20180836</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Acne Keloid - etiology ; Acne Keloid - surgery ; Acne Vulgaris - complications ; Acne Vulgaris - drug therapy ; Administration, Oral ; Adolescent ; Adult ; Biological and medical sciences ; Cicatrix, Hypertrophic - etiology ; Cicatrix, Hypertrophic - surgery ; Combined Modality Therapy ; Dermabrasion - methods ; Dermatologic Agents - administration & dosage ; Dermatology ; Face ; Female ; Humans ; Isotretinoin - administration & dosage ; Isotretinoin - adverse effects ; Male ; Medical sciences ; Patient Satisfaction ; Prospective Studies ; Skin involvement in other diseases. Miscellaneous. General aspects ; Skin plastic surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Treatment Outcome ; Wound Healing ; Young Adult</subject><ispartof>Dermatologic surgery, 2010-04, Vol.36 (4), p.483-489</ispartof><rights>2010 by the American Society for Dermatologic Surgery, Inc.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3984-de5b77992d56451a0d7a4b378320fa58ae27db949ee0628654aae9bec55171793</citedby><cites>FETCH-LOGICAL-c3984-de5b77992d56451a0d7a4b378320fa58ae27db949ee0628654aae9bec55171793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1524-4725.2010.01474.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1524-4725.2010.01474.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22752303$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20180836$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BAGATIN, EDILÉIA</creatorcontrib><creatorcontrib>DOS SANTOS GUADANHIM, LILIA RAMOS</creatorcontrib><creatorcontrib>YARAK, SAMIRA</creatorcontrib><creatorcontrib>KAMAMOTO, CRISTHINE SOUZA LEÃO</creatorcontrib><creatorcontrib>DE ALMEIDA, FERNANDO AUGUSTO</creatorcontrib><title>Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin</title><title>Dermatologic surgery</title><addtitle>Dermatol Surg</addtitle><description>BACKGROUND
Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommended 6 to 12 months from the end of oral isotretinoin treatment.
OBJECTIVE
To evaluate wound healing after localized dermabrasion in patients receiving oral isotretinoin.
MATERIALS & METHODS
Interventional, prospective study involving seven patients taking oral isotretinoin to treat acne and with atrophic acne scars on the face. Manual dermabrasion was performed on all patients in an area of approximately 1 cm2, and a 6‐month reepithelization follow‐up by clinical evaluation was conducted.
RESULTS
All patients presented normal cicatrization evolution; hypertrophic scarring or keloid as a result of localized abrasion was not observed, and atrophic acne scar revision result was excellent.
CONCLUSION
The current recommendation to wait 6 to 12 months after treatment with oral isotretinoin for acne scar revision using dermabrasion should be re‐evaluated. Abrasion of a small test area may be a useful predictor of wound healing, enabling earlier acne scar treatment using this procedure.
The authors have indicated no significant interest with commercial supporters.</description><subject>Acne Keloid - etiology</subject><subject>Acne Keloid - surgery</subject><subject>Acne Vulgaris - complications</subject><subject>Acne Vulgaris - drug therapy</subject><subject>Administration, Oral</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cicatrix, Hypertrophic - etiology</subject><subject>Cicatrix, Hypertrophic - surgery</subject><subject>Combined Modality Therapy</subject><subject>Dermabrasion - methods</subject><subject>Dermatologic Agents - administration & dosage</subject><subject>Dermatology</subject><subject>Face</subject><subject>Female</subject><subject>Humans</subject><subject>Isotretinoin - administration & dosage</subject><subject>Isotretinoin - adverse effects</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Patient Satisfaction</subject><subject>Prospective Studies</subject><subject>Skin involvement in other diseases. Miscellaneous. General aspects</subject><subject>Skin plastic surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Treatment Outcome</subject><subject>Wound Healing</subject><subject>Young Adult</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkD1v2zAQhomgRZ24_QsFl6KTXH6K5NAhsJM0QIAMTmbiJJ1SGvpISRm2_32k2HXXcuGB97zHw0MI5WzBx_Njs-BaqEwZoReCja-MK6MW-wtyeW58GGtm8oxpLmbkKqUNY1w4yT6R2ZixzMr8kixXGFsoIqTQd7TuI70uO6TrEmKiq20M3Qt9ighDi91Ad2H4TR8jNPQ-9UPEIXR96D6TjzU0Cb-c7jl5vr15Wv7KHh7v7pfXD1kpnVVZhbowxjlR6VxpDqwyoApprBSsBm0BhakKpxwiy4XNtQJAV2CpNTfcODkn349zX2P_Z4tp8G1IJTYNdNhvkzdSWmdzMZH2SJaxTyli7V9jaCEePGd-Mug3fhLlJ1F-MujfDfr9GP16-mRbtFidg3-VjcC3EwCphKaO0JUh_eOE0UIyOXI_j9wuNHj47wX8av08VfINVVKKug</recordid><startdate>201004</startdate><enddate>201004</enddate><creator>BAGATIN, EDILÉIA</creator><creator>DOS SANTOS GUADANHIM, LILIA RAMOS</creator><creator>YARAK, SAMIRA</creator><creator>KAMAMOTO, CRISTHINE SOUZA LEÃO</creator><creator>DE ALMEIDA, FERNANDO AUGUSTO</creator><general>Blackwell Publishing Inc</general><general>Wiley</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201004</creationdate><title>Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin</title><author>BAGATIN, EDILÉIA ; DOS SANTOS GUADANHIM, LILIA RAMOS ; YARAK, SAMIRA ; KAMAMOTO, CRISTHINE SOUZA LEÃO ; DE ALMEIDA, FERNANDO AUGUSTO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3984-de5b77992d56451a0d7a4b378320fa58ae27db949ee0628654aae9bec55171793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Acne Keloid - etiology</topic><topic>Acne Keloid - surgery</topic><topic>Acne Vulgaris - complications</topic><topic>Acne Vulgaris - drug therapy</topic><topic>Administration, Oral</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cicatrix, Hypertrophic - etiology</topic><topic>Cicatrix, Hypertrophic - surgery</topic><topic>Combined Modality Therapy</topic><topic>Dermabrasion - methods</topic><topic>Dermatologic Agents - administration & dosage</topic><topic>Dermatology</topic><topic>Face</topic><topic>Female</topic><topic>Humans</topic><topic>Isotretinoin - administration & dosage</topic><topic>Isotretinoin - adverse effects</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Patient Satisfaction</topic><topic>Prospective Studies</topic><topic>Skin involvement in other diseases. Miscellaneous. General aspects</topic><topic>Skin plastic surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Treatment Outcome</topic><topic>Wound Healing</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BAGATIN, EDILÉIA</creatorcontrib><creatorcontrib>DOS SANTOS GUADANHIM, LILIA RAMOS</creatorcontrib><creatorcontrib>YARAK, SAMIRA</creatorcontrib><creatorcontrib>KAMAMOTO, CRISTHINE SOUZA LEÃO</creatorcontrib><creatorcontrib>DE ALMEIDA, FERNANDO AUGUSTO</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BAGATIN, EDILÉIA</au><au>DOS SANTOS GUADANHIM, LILIA RAMOS</au><au>YARAK, SAMIRA</au><au>KAMAMOTO, CRISTHINE SOUZA LEÃO</au><au>DE ALMEIDA, FERNANDO AUGUSTO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2010-04</date><risdate>2010</risdate><volume>36</volume><issue>4</issue><spage>483</spage><epage>489</epage><pages>483-489</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>BACKGROUND
Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommended 6 to 12 months from the end of oral isotretinoin treatment.
OBJECTIVE
To evaluate wound healing after localized dermabrasion in patients receiving oral isotretinoin.
MATERIALS & METHODS
Interventional, prospective study involving seven patients taking oral isotretinoin to treat acne and with atrophic acne scars on the face. Manual dermabrasion was performed on all patients in an area of approximately 1 cm2, and a 6‐month reepithelization follow‐up by clinical evaluation was conducted.
RESULTS
All patients presented normal cicatrization evolution; hypertrophic scarring or keloid as a result of localized abrasion was not observed, and atrophic acne scar revision result was excellent.
CONCLUSION
The current recommendation to wait 6 to 12 months after treatment with oral isotretinoin for acne scar revision using dermabrasion should be re‐evaluated. Abrasion of a small test area may be a useful predictor of wound healing, enabling earlier acne scar treatment using this procedure.
The authors have indicated no significant interest with commercial supporters.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>20180836</pmid><doi>10.1111/j.1524-4725.2010.01474.x</doi><tpages>7</tpages></addata></record> |
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| ispartof | Dermatologic surgery, 2010-04, Vol.36 (4), p.483-489 |
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| subjects | Acne Keloid - etiology Acne Keloid - surgery Acne Vulgaris - complications Acne Vulgaris - drug therapy Administration, Oral Adolescent Adult Biological and medical sciences Cicatrix, Hypertrophic - etiology Cicatrix, Hypertrophic - surgery Combined Modality Therapy Dermabrasion - methods Dermatologic Agents - administration & dosage Dermatology Face Female Humans Isotretinoin - administration & dosage Isotretinoin - adverse effects Male Medical sciences Patient Satisfaction Prospective Studies Skin involvement in other diseases. Miscellaneous. General aspects Skin plastic surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Treatment Outcome Wound Healing Young Adult |
| title | Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin |
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