Gastric emptying evaluation in children with erosive gastroesophageal reflux disease

Background/aims Delayed gastric emptying may be an important contributing factor to gastroesophageal reflux disease (GERD) in children, but there are limited data on its evaluation in children with erosive-GERD. This study aims to evaluate the gastric emptying of a solid meal in patients with erosiv...

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Veröffentlicht in:Pediatric surgery international 2010-05, Vol.26 (5), p.473-478
Hauptverfasser: Machado, Rodrigo Strehl, Yamamoto, Érica, da Silva Patrício, Francy Reis, Reber, Marialice, Kawakami, Elisabete
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container_end_page 478
container_issue 5
container_start_page 473
container_title Pediatric surgery international
container_volume 26
creator Machado, Rodrigo Strehl
Yamamoto, Érica
da Silva Patrício, Francy Reis
Reber, Marialice
Kawakami, Elisabete
description Background/aims Delayed gastric emptying may be an important contributing factor to gastroesophageal reflux disease (GERD) in children, but there are limited data on its evaluation in children with erosive-GERD. This study aims to evaluate the gastric emptying of a solid meal in patients with erosive-GERD. Methods Nineteen patients (age range 8.79–17.9 years) with erosive esophagitis and 14 healthy controls (age range from 8.04 to 18.7 years) were compared. Esophagitis was graded according to Los Angeles classification. The gastric emptying was evaluated by 13 C-octanoic breath test, which was performed after a 344 kcal standardized solid test meal. Symptoms were evaluated using a standardized questionnaire. Results The two most prevalent symptoms were nausea and epigastric pain, which were reported by 12 (63.2%) patients. Irritable bowel syndrome was present in 26.3% (5/19). The median gastric emptying half-time in patients was 160 min (interquartile range [IQR] 140–174 min), which was not different from the controls’ figure (median 157 min, IQR 143–170 min). Additionally, the lag time and the gastric emptying coefficient were not significantly different between the study groups. Conclusion Delayed gastric emptying is not associated with erosive esophagitis in children with GERD, when compared to controls.
doi_str_mv 10.1007/s00383-010-2579-4
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Conclusion Delayed gastric emptying is not associated with erosive esophagitis in children with GERD, when compared to controls.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>20405273</pmid><doi>10.1007/s00383-010-2579-4</doi><tpages>6</tpages></addata></record>
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subjects Adolescent
Breath Tests
Case-Control Studies
Chi-Square Distribution
Child
Endoscopy, Digestive System
Female
Gastric Emptying
Gastroesophageal Reflux - physiopathology
Humans
Male
Medicine
Medicine & Public Health
Original Article
Pediatric Surgery
Pediatrics
Statistics, Nonparametric
Surgery
Surveys and Questionnaires
title Gastric emptying evaluation in children with erosive gastroesophageal reflux disease
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