The diagnostic role of dual femur bone density measurement in low-impact fractures
A high correlation has been documented between the left and right femoral bone mineral densities in the normal population. This suggests that dual femur measurements are not justified in clinical practice. This study evaluated whether this premise holds for subjects who have lost bone mass and have...
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| Veröffentlicht in: | Osteoporosis international 2003-06, Vol.14 (4), p.339-344 |
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| creator | WONG, Joseph C. H MCEWAN, Louise LEE, Naomi GRIFFITHS, Matthew R POCOCK, Nicholas A |
| description | A high correlation has been documented between the left and right femoral bone mineral densities in the normal population. This suggests that dual femur measurements are not justified in clinical practice. This study evaluated whether this premise holds for subjects who have lost bone mass and have sustained fractures with minimal trauma. Seventy-eight women aged 31-83 years (mean=66 years) with previous low-impact fractures had both proximal femora measured using dual-energy X-ray absorptiometry. There were significant correlations between values in the left and right total hip (TH) (r=0.95; p |
| doi_str_mv | 10.1007/s00198-003-1378-3 |
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H ; MCEWAN, Louise ; LEE, Naomi ; GRIFFITHS, Matthew R ; POCOCK, Nicholas A</creator><creatorcontrib>WONG, Joseph C. H ; MCEWAN, Louise ; LEE, Naomi ; GRIFFITHS, Matthew R ; POCOCK, Nicholas A</creatorcontrib><description>A high correlation has been documented between the left and right femoral bone mineral densities in the normal population. This suggests that dual femur measurements are not justified in clinical practice. This study evaluated whether this premise holds for subjects who have lost bone mass and have sustained fractures with minimal trauma. Seventy-eight women aged 31-83 years (mean=66 years) with previous low-impact fractures had both proximal femora measured using dual-energy X-ray absorptiometry. There were significant correlations between values in the left and right total hip (TH) (r=0.95; p<0.05) and in the left and right femoral neck (FN) (r=0.90; p<0.05). The mean differences between the left and right TH and FN densities were not significant. However, the range of the limits of agreement for the TH (-0.074 to 0.086 g/cm2) and FN (-0.115 to 0.105 g/cm2) were greater than the 95% confidence interval for true change for the TH (0.05 g/cm2) and FN (0.07 g/cm2). Any longitudinal BMD assessment therefore needs to measure the same proximal femur to get a reliable comparison. A one-tailed analysis showed that for the TH, 7.5% of subjects had a T-score discordance greater than or equal to 0.5 and 0.5% had a T-score discordance greater than or equal to 1. For the FN, 9% had a T-score discordance greater than or equal to 0.5 and 2.5% had a T-score discordance greater than or equal to 1. The use of dual femur measurements increases the diagnostic yield by about 10% in subjects with prior minimal trauma fractures.</description><identifier>ISSN: 0937-941X</identifier><identifier>EISSN: 1433-2965</identifier><identifier>DOI: 10.1007/s00198-003-1378-3</identifier><identifier>PMID: 12730738</identifier><language>eng</language><publisher>London: Springer</publisher><subject>Absorptiometry, Photon - methods ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Bone Density - physiology ; Female ; Femur - diagnostic imaging ; Femur - physiopathology ; Hip Fractures - prevention & control ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Middle Aged ; Osteoarticular system. Muscles ; Predictive Value of Tests ; Radiodiagnosis. Nmr imagery. 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H</creatorcontrib><creatorcontrib>MCEWAN, Louise</creatorcontrib><creatorcontrib>LEE, Naomi</creatorcontrib><creatorcontrib>GRIFFITHS, Matthew R</creatorcontrib><creatorcontrib>POCOCK, Nicholas A</creatorcontrib><title>The diagnostic role of dual femur bone density measurement in low-impact fractures</title><title>Osteoporosis international</title><addtitle>Osteoporos Int</addtitle><description>A high correlation has been documented between the left and right femoral bone mineral densities in the normal population. This suggests that dual femur measurements are not justified in clinical practice. This study evaluated whether this premise holds for subjects who have lost bone mass and have sustained fractures with minimal trauma. Seventy-eight women aged 31-83 years (mean=66 years) with previous low-impact fractures had both proximal femora measured using dual-energy X-ray absorptiometry. There were significant correlations between values in the left and right total hip (TH) (r=0.95; p<0.05) and in the left and right femoral neck (FN) (r=0.90; p<0.05). The mean differences between the left and right TH and FN densities were not significant. However, the range of the limits of agreement for the TH (-0.074 to 0.086 g/cm2) and FN (-0.115 to 0.105 g/cm2) were greater than the 95% confidence interval for true change for the TH (0.05 g/cm2) and FN (0.07 g/cm2). Any longitudinal BMD assessment therefore needs to measure the same proximal femur to get a reliable comparison. A one-tailed analysis showed that for the TH, 7.5% of subjects had a T-score discordance greater than or equal to 0.5 and 0.5% had a T-score discordance greater than or equal to 1. For the FN, 9% had a T-score discordance greater than or equal to 0.5 and 2.5% had a T-score discordance greater than or equal to 1. The use of dual femur measurements increases the diagnostic yield by about 10% in subjects with prior minimal trauma fractures.</description><subject>Absorptiometry, Photon - methods</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Bone Density - physiology</subject><subject>Female</subject><subject>Femur - diagnostic imaging</subject><subject>Femur - physiopathology</subject><subject>Hip Fractures - prevention & control</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Osteoarticular system. Muscles</subject><subject>Predictive Value of Tests</subject><subject>Radiodiagnosis. Nmr imagery. 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H ; MCEWAN, Louise ; LEE, Naomi ; GRIFFITHS, Matthew R ; POCOCK, Nicholas A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-b4ba2cfc4ee3f323954112d7bd2f7385d074a291c3992b8c0b03dfed27d082f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Absorptiometry, Photon - methods</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Bone Density - physiology</topic><topic>Female</topic><topic>Femur - diagnostic imaging</topic><topic>Femur - physiopathology</topic><topic>Hip Fractures - prevention & control</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Osteoarticular system. Muscles</topic><topic>Predictive Value of Tests</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WONG, Joseph C. H</creatorcontrib><creatorcontrib>MCEWAN, Louise</creatorcontrib><creatorcontrib>LEE, Naomi</creatorcontrib><creatorcontrib>GRIFFITHS, Matthew R</creatorcontrib><creatorcontrib>POCOCK, Nicholas A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Physical Education Index</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (Proquest)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Osteoporosis international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WONG, Joseph C. H</au><au>MCEWAN, Louise</au><au>LEE, Naomi</au><au>GRIFFITHS, Matthew R</au><au>POCOCK, Nicholas A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The diagnostic role of dual femur bone density measurement in low-impact fractures</atitle><jtitle>Osteoporosis international</jtitle><addtitle>Osteoporos Int</addtitle><date>2003-06-01</date><risdate>2003</risdate><volume>14</volume><issue>4</issue><spage>339</spage><epage>344</epage><pages>339-344</pages><issn>0937-941X</issn><eissn>1433-2965</eissn><abstract>A high correlation has been documented between the left and right femoral bone mineral densities in the normal population. This suggests that dual femur measurements are not justified in clinical practice. This study evaluated whether this premise holds for subjects who have lost bone mass and have sustained fractures with minimal trauma. Seventy-eight women aged 31-83 years (mean=66 years) with previous low-impact fractures had both proximal femora measured using dual-energy X-ray absorptiometry. There were significant correlations between values in the left and right total hip (TH) (r=0.95; p<0.05) and in the left and right femoral neck (FN) (r=0.90; p<0.05). The mean differences between the left and right TH and FN densities were not significant. However, the range of the limits of agreement for the TH (-0.074 to 0.086 g/cm2) and FN (-0.115 to 0.105 g/cm2) were greater than the 95% confidence interval for true change for the TH (0.05 g/cm2) and FN (0.07 g/cm2). Any longitudinal BMD assessment therefore needs to measure the same proximal femur to get a reliable comparison. A one-tailed analysis showed that for the TH, 7.5% of subjects had a T-score discordance greater than or equal to 0.5 and 0.5% had a T-score discordance greater than or equal to 1. For the FN, 9% had a T-score discordance greater than or equal to 0.5 and 2.5% had a T-score discordance greater than or equal to 1. The use of dual femur measurements increases the diagnostic yield by about 10% in subjects with prior minimal trauma fractures.</abstract><cop>London</cop><pub>Springer</pub><pmid>12730738</pmid><doi>10.1007/s00198-003-1378-3</doi><tpages>6</tpages></addata></record> |
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| subjects | Absorptiometry, Photon - methods Adult Aged Aged, 80 and over Biological and medical sciences Bone Density - physiology Female Femur - diagnostic imaging Femur - physiopathology Hip Fractures - prevention & control Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Middle Aged Osteoarticular system. Muscles Predictive Value of Tests Radiodiagnosis. Nmr imagery. Nmr spectrometry |
| title | The diagnostic role of dual femur bone density measurement in low-impact fractures |
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