role of Sov protein in the secretion of gingipain protease virulence factors of Porphyromonas gingivalis

Porphyromonas gingivalis transports Arg-gingipains and Lys-gingipain across the outer membrane via an unknown pathway. Recently, we found that the sov gene of P. gingivalis W83 was required for this step. In the present study, we characterized the Sov protein. We constructed a P. gingivalis strain t...

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Veröffentlicht in:	FEMS microbiology letters 2010, Vol.302 (2), p.166-174
Hauptverfasser:	Saiki, Keitarou, Konishi, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - isolation & purification Adhesins, Bacterial - metabolism Bacterial Proteins - isolation & purification Bacterial Proteins - metabolism Biological and medical sciences C-Terminus Cell Membrane - chemistry Clonal deletion Cysteine Endopeptidases - isolation & purification Cysteine Endopeptidases - metabolism Fundamental and applied biological sciences. Psychology Gingipain Histidine Immunoglobulins Membrane proteins Membranes Microbiology Porphyromonas gingivalis Porphyromonas gingivalis - chemistry Porphyromonas gingivalis - metabolism protein secretion Protein Transport Proteins Sequence Deletion Virulence Virulence factors Virulence Factors - isolation & purification Virulence Factors - metabolism
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