Nicotine-induced conditioned place preference in rats: Sex differences and the role of mGluR5 receptors

To elucidate sex differences in nicotine addiction and the underlying mechanisms of the conditioning aspects of nicotine, nicotine-induced conditioned place preference (CPP) was evaluated in male and female Sprague Dawley rats using a three-chambered CPP apparatus and a biased design. In a series of...

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Veröffentlicht in:	Neuropharmacology 2010-02, Vol.58 (2), p.374-382
Hauptverfasser:	Yararbas, Gorkem, Keser, Aysegul, Kanit, Lutfiye, Pogun, Sakire
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Animals Automation Conditioned place preference Conditioning, Classical - drug effects Conditioning, Classical - physiology Dose-Response Relationship, Drug Excitatory Amino Acid Antagonists - pharmacology Female Male mGluR5 MPEP Neuropsychological Tests Nicotine Nicotine - administration & dosage Nicotine - pharmacology Nicotinic Agonists - administration & dosage Nicotinic Agonists - pharmacology Pyridines - pharmacology Rats Rats, Sprague-Dawley Receptor, Metabotropic Glutamate 5 Receptors, Metabotropic Glutamate - antagonists & inhibitors Receptors, Metabotropic Glutamate - metabolism Reproducibility of Results Sex Characteristics Sex differences Space Perception - drug effects Space Perception - physiology
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