Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia-reperfusion-induced acute kidney injury

Aim: Diabetic patients are at higher risk of failure to recover after acute kidney injury, however, the mechanism and therapeutic strategies remain unclear. Erythropoietin is cytoprotective in a variety of non‐haematopoietic cells. The aim of the present study was to clarify the mechanism of diabet...

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Veröffentlicht in:	Nephrology (Carlton, Vic.) Vic.), 2010-02, Vol.15 (1), p.93-101
Hauptverfasser:	NAKAZAWA, JUN, ISSHIKI, KEIJI, SUGIMOTO, TOSHIRO, ARAKI, SHIN-ICHI, KUME, SHINJI, YOKOMAKU, YUKIYO, CHIN-KANASAKI, MASAMI, SAKAGUCHI, MASAYOSHI, KOYA, DAISUKE, HANEDA, MASAKAZU, KASHIWAGI, ATSUNORI, UZU, TAKASHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - etiology Acute Kidney Injury - prevention & control acute tubular necrosis Animals apoptosis Asialoglycoproteins - therapeutic use bone morphogenetic protein Diabetes Mellitus, Experimental - complications erythropoietin Erythropoietin - analogs & derivatives Erythropoietin - therapeutic use fibrosis ischaemia-reperfusion Male Mice Mice, Inbred C57BL Reperfusion Injury - complications
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