Decline in CTL and antibody responses to HIV-1 p17 and p24 antigens in HIV-1-infected hemophiliacs irrespective of disease progression. A 5-year follow-up study

CTL and antibody responses to HIV-1 p17 and p24 antigens were monitored from 1986-1991, in 4 hemophiliacs. The patients had been infected with HIV-1 between 1980 and 1984. Two patients have remained asymptomatic while two progressed to AIDS in 1990. CTL were boosted by culturing with peptides from p...

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Veröffentlicht in:	AIDS research and human retroviruses 1992-08, Vol.8 (8), p.1361-1368
Hauptverfasser:	O'TOOLE, C. M, GRAHAM, S, LOWDELL, M. W, CHARGELEGUE, D, MARSDEN, H, COLVIN, B. T
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Biological and medical sciences Cell Line, Transformed Epitopes - immunology Follow-Up Studies gag Gene Products, Human Immunodeficiency Virus Gene Products, gag - immunology Hemophilia A - complications HIV Antibodies - biosynthesis HIV Antibodies - blood HIV Antigens - immunology HIV Core Protein p24 - immunology HIV Infections - complications HIV Infections - immunology HIV-1 - immunology human immunodeficiency virus 1 Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Medical sciences Peptide Fragments - immunology T-Lymphocytes, Cytotoxic - immunology Viral Proteins
Online-Zugang:	Volltext
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