Turbulent Flow Chromatography TFC-tandem mass spectrometry supporting in vitro/ vivo studies of NCEs in high throughput fashion

Turbulent Flow Chromatography (TFC) is a powerful approach for on-line extraction in bioanalytical studies. It improves sensitivity and reduces sample preparation time, two factors that are of primary importance in drug discovery. In this paper the application of the ARIA system to the analytical su...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2010-03, Vol.51 (4), p.834-841
Hauptverfasser:	Verdirame, Maria, Veneziano, Maria, Alfieri, Anna, Di Marco, Annalise, Monteagudo, Edith, Bonelli, Fabio
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Chromatography - instrumentation Equipment Design Fundamental and applied biological sciences. Psychology General pharmacology Hepatocytes - metabolism High-Throughput Screening Assays - instrumentation Humans Medical sciences On-line extraction Online Systems - instrumentation Pharmaceutical Preparations - blood Pharmaceutical Preparations - metabolism Pharmacokinetics Pharmacology. Drug treatments Rats Reproducibility of Results Spectrometry, Mass, Electrospray Ionization - instrumentation Tandem Mass Spectrometry - instrumentation TFC-LC–MS/MS
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!