The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs

The impact of excess dietary leucine (Leu) was studied in two growth assays with pigs (8–25 kg). In each trial, forty-eight pigs were allotted to one of six dietary groups. The dietary Leu supply increased from treatment L100 to L200 (three increments). To guarantee that interactions between the bra...

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Veröffentlicht in:	British journal of nutrition 2010-04, Vol.103 (7), p.964-976
Hauptverfasser:	Wiltafsky, Markus Karl, Pfaffl, Michael Walter, Roth, Franz Xaver
Format:	Artikel
Sprache:	eng
Schlagworte:	3-methyl-2-oxobutanoate dehydrogenase (lipoamide) 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) - metabolism Amino acid interactions amino acid metabolism Amino acids Amino Acids, Branched-Chain - blood Amino Acids, Branched-Chain - metabolism Amino Acids, Branched-Chain - pharmacology Analysis of Variance animal growth animal nutrition animal performance Animals Biological and medical sciences blood plasma branched chain amino acids Branched-chain α-keto acid dehydrogenase Diet dose response Dose-Response Relationship, Drug enzyme activity enzyme kinetics Enzymes Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gene Expression Profiling Hogs hormone receptors insulin-like growth factor I isoleucine Isoleucine - blood Isoleucine - metabolism Isoleucine - pharmacology Keto Acids - blood Kinetics leucine Leucine - blood Leucine - metabolism Leucine - pharmacology Leucine excess Linear Models liver Liver - metabolism messenger RNA Metabolism Metabolism - drug effects Metabolism and Metabolic Studies Metabolites nutrient excess nutrient-nutrient interactions Nutrition research Pigs Receptors, Somatotropin - genetics Receptors, Somatotropin - metabolism RNA, Messenger - metabolism Somatomedins - genetics Somatomedins - metabolism Swine Swine - growth & development Swine - metabolism swine feeding transcriptome valine Valine - blood Valine - metabolism Valine - pharmacology Vertebrates: anatomy and physiology, studies on body, several organs or systems Weaning young animals
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