The application of fully automated on-line solid phase extraction in bioanalysis

This paper describes the application of fully automated on-line solid phase extraction to the bioanalysis of three example compounds using the Symbiosis platform. The on-line assay performance is compared to off-line methodologies for the same compounds. The three example compounds possess a variety...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2010-05, Vol.52 (1), p.86-92
Hauptverfasser:	Mitchell, Richard J., Christian, Rachelle, Hughes, Heather, Miah, Asadh, Walker, Donald K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical, structural and metabolic biochemistry Automation, Laboratory Bioanalysis Biological and medical sciences Candoxatril Chromatography, Reverse-Phase Fluconazole Fluconazole - blood Fundamental and applied biological sciences. Psychology General pharmacology Humans Indans - blood Mass Spectrometry Medical sciences On-line solid phase extraction Online Systems Pharmacology. Drug treatments Propionates - blood Reproducibility of Results Solid Phase Extraction Symbiosis Technology, Pharmaceutical - methods Temperature
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