Glycolic acid induces keratinocyte proliferation in a skin equivalent model via TRPV1 activation

Abstract Background Glycolic acid (GA) is the most commonly used alpha-hydroxy acid (AHA) for dermatologic applications, and is considered as a versatile superficial peeling agent for facial rejuvenation. Its therapeutic effect includes acceleration of epidermal turnover without apparent inflammatio...

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Veröffentlicht in:	Journal of dermatological science 2010-02, Vol.57 (2), p.108-113
Hauptverfasser:	Denda, Sumiko, Denda, Mitsuhiro, Inoue, Kaori, Hibino, Toshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism AHA ATP Calcium - metabolism Capsaicin - analogs & derivatives Capsaicin - pharmacology Cell Proliferation - drug effects Cells, Cultured Chemical peeling Dermatology Diterpenes - pharmacology Glycolates - pharmacology Glycolic acid Humans Immunohistochemistry Keratinocytes - cytology Keratinocytes - metabolism Skin, Artificial TRPV Cation Channels - antagonists & inhibitors TRPV Cation Channels - metabolism TRPV1
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