Clinical study on acute kidney injury after myeloablative allogeneic hematopoietic cell transplantation
To explore the incidence, pathogenesis, risk factors, prophylaxis and treatment of acute kidney injury (AKI) after myeloablative allogeneic hematopoietic stem cell transplantation (allo-HSCT). Clinical data of 120 patients received myeloablative allo-HSCT were retrospectively analyzed. Serum creatin...
Gespeichert in:
| Veröffentlicht in: | Zhōnghuá xuèyèxué zázhì 2008-06, Vol.29 (6), p.401-404 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | chi |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 404 |
|---|---|
| container_issue | 6 |
| container_start_page | 401 |
| container_title | Zhōnghuá xuèyèxué zázhì |
| container_volume | 29 |
| creator | Bao, Yu-shi Jiang, Er-lie Wang, Mei Huang, Yong Wei, Jia-lin Yang, Dong-lin Feng, Si-zhou Han, Ming-zhe |
| description | To explore the incidence, pathogenesis, risk factors, prophylaxis and treatment of acute kidney injury (AKI) after myeloablative allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Clinical data of 120 patients received myeloablative allo-HSCT were retrospectively analyzed.
Serum creatinine level in the patients showed significantly higher than baseline value at 28-60 days after transplantation (P |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_733861652</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733861652</sourcerecordid><originalsourceid>FETCH-LOGICAL-p125t-3d60cd78515d720efba9ed463996224ff12f2d0d2e0cc75bce1c817f9962dcb73</originalsourceid><addsrcrecordid>eNo1kE1LxDAYhHNQ3GXdvyC5eSrko2naoxS_YGEvei5p8maNpkltUqH_3i6up2GYh2GYK7QlTPCCSSY3aJ-S64mgvKo5JzdoQxvCqSzLLTq13gWnlccpz2bBMWCl5wz4y5kAC3bhc54WrGyGCQ8L-Kh6r7L7Aay8jycI4DT-gEHlOEYHeXUavMd5UiGNXoW80jHcomurfIL9RXfo_enxrX0pDsfn1_bhUIyUiVxwUxFtZC2oMJIRsL1qwJQVb5qKsdJayiwzxDAgWkvRa6C6ptKeY6N7yXfo_q93nOL3DCl3g0vnQSpAnFMnOa8rWgm2kncXcu4HMN04uUFNS_f_Df8FEwtizQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733861652</pqid></control><display><type>article</type><title>Clinical study on acute kidney injury after myeloablative allogeneic hematopoietic cell transplantation</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Bao, Yu-shi ; Jiang, Er-lie ; Wang, Mei ; Huang, Yong ; Wei, Jia-lin ; Yang, Dong-lin ; Feng, Si-zhou ; Han, Ming-zhe</creator><creatorcontrib>Bao, Yu-shi ; Jiang, Er-lie ; Wang, Mei ; Huang, Yong ; Wei, Jia-lin ; Yang, Dong-lin ; Feng, Si-zhou ; Han, Ming-zhe</creatorcontrib><description>To explore the incidence, pathogenesis, risk factors, prophylaxis and treatment of acute kidney injury (AKI) after myeloablative allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Clinical data of 120 patients received myeloablative allo-HSCT were retrospectively analyzed.
Serum creatinine level in the patients showed significantly higher than baseline value at 28-60 days after transplantation (P<0.05). 73 patients (60.8%) developed AKI at a median of 33 days after allo-HSCT, including grade 2 in 32 patients (26.7%). Patients with grade 1 AKI showed significant higher serum cyclosporine A (CsA) levels (P<0.05). Hepatic veno-occlusive disease( HVOD), acute graft-versus-host disease (aGVHD) and total bilirubin > 40 micromol/L were high risk factors of occurring AKI (P<0.05). 19 patients died within 100 days after allo-HSCT, grade 2 AKI was a high risk factor of mortality (P< 0.05). 180-day survival rate was significantly lower in patients with grade 2 AKI after allo-HSCT (P<0.05).
AKI is one of the</description><identifier>ISSN: 0253-2727</identifier><identifier>PMID: 19031744</identifier><language>chi</language><publisher>China</publisher><subject>Acute Kidney Injury - etiology ; Acute Kidney Injury - prevention & control ; Adolescent ; Adult ; Female ; Hematopoietic Stem Cell Transplantation ; Humans ; Male ; Middle Aged ; Postoperative Complications - prevention & control ; Retrospective Studies ; Risk Factors ; Transplantation Conditioning ; Transplantation, Homologous ; Young Adult</subject><ispartof>Zhōnghuá xuèyèxué zázhì, 2008-06, Vol.29 (6), p.401-404</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19031744$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bao, Yu-shi</creatorcontrib><creatorcontrib>Jiang, Er-lie</creatorcontrib><creatorcontrib>Wang, Mei</creatorcontrib><creatorcontrib>Huang, Yong</creatorcontrib><creatorcontrib>Wei, Jia-lin</creatorcontrib><creatorcontrib>Yang, Dong-lin</creatorcontrib><creatorcontrib>Feng, Si-zhou</creatorcontrib><creatorcontrib>Han, Ming-zhe</creatorcontrib><title>Clinical study on acute kidney injury after myeloablative allogeneic hematopoietic cell transplantation</title><title>Zhōnghuá xuèyèxué zázhì</title><addtitle>Zhonghua Xue Ye Xue Za Zhi</addtitle><description>To explore the incidence, pathogenesis, risk factors, prophylaxis and treatment of acute kidney injury (AKI) after myeloablative allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Clinical data of 120 patients received myeloablative allo-HSCT were retrospectively analyzed.
Serum creatinine level in the patients showed significantly higher than baseline value at 28-60 days after transplantation (P<0.05). 73 patients (60.8%) developed AKI at a median of 33 days after allo-HSCT, including grade 2 in 32 patients (26.7%). Patients with grade 1 AKI showed significant higher serum cyclosporine A (CsA) levels (P<0.05). Hepatic veno-occlusive disease( HVOD), acute graft-versus-host disease (aGVHD) and total bilirubin > 40 micromol/L were high risk factors of occurring AKI (P<0.05). 19 patients died within 100 days after allo-HSCT, grade 2 AKI was a high risk factor of mortality (P< 0.05). 180-day survival rate was significantly lower in patients with grade 2 AKI after allo-HSCT (P<0.05).
AKI is one of the</description><subject>Acute Kidney Injury - etiology</subject><subject>Acute Kidney Injury - prevention & control</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Female</subject><subject>Hematopoietic Stem Cell Transplantation</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications - prevention & control</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Transplantation Conditioning</subject><subject>Transplantation, Homologous</subject><subject>Young Adult</subject><issn>0253-2727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kE1LxDAYhHNQ3GXdvyC5eSrko2naoxS_YGEvei5p8maNpkltUqH_3i6up2GYh2GYK7QlTPCCSSY3aJ-S64mgvKo5JzdoQxvCqSzLLTq13gWnlccpz2bBMWCl5wz4y5kAC3bhc54WrGyGCQ8L-Kh6r7L7Aay8jycI4DT-gEHlOEYHeXUavMd5UiGNXoW80jHcomurfIL9RXfo_enxrX0pDsfn1_bhUIyUiVxwUxFtZC2oMJIRsL1qwJQVb5qKsdJayiwzxDAgWkvRa6C6ptKeY6N7yXfo_q93nOL3DCl3g0vnQSpAnFMnOa8rWgm2kncXcu4HMN04uUFNS_f_Df8FEwtizQ</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>Bao, Yu-shi</creator><creator>Jiang, Er-lie</creator><creator>Wang, Mei</creator><creator>Huang, Yong</creator><creator>Wei, Jia-lin</creator><creator>Yang, Dong-lin</creator><creator>Feng, Si-zhou</creator><creator>Han, Ming-zhe</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200806</creationdate><title>Clinical study on acute kidney injury after myeloablative allogeneic hematopoietic cell transplantation</title><author>Bao, Yu-shi ; Jiang, Er-lie ; Wang, Mei ; Huang, Yong ; Wei, Jia-lin ; Yang, Dong-lin ; Feng, Si-zhou ; Han, Ming-zhe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p125t-3d60cd78515d720efba9ed463996224ff12f2d0d2e0cc75bce1c817f9962dcb73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2008</creationdate><topic>Acute Kidney Injury - etiology</topic><topic>Acute Kidney Injury - prevention & control</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Female</topic><topic>Hematopoietic Stem Cell Transplantation</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications - prevention & control</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Transplantation Conditioning</topic><topic>Transplantation, Homologous</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Bao, Yu-shi</creatorcontrib><creatorcontrib>Jiang, Er-lie</creatorcontrib><creatorcontrib>Wang, Mei</creatorcontrib><creatorcontrib>Huang, Yong</creatorcontrib><creatorcontrib>Wei, Jia-lin</creatorcontrib><creatorcontrib>Yang, Dong-lin</creatorcontrib><creatorcontrib>Feng, Si-zhou</creatorcontrib><creatorcontrib>Han, Ming-zhe</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhōnghuá xuèyèxué zázhì</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bao, Yu-shi</au><au>Jiang, Er-lie</au><au>Wang, Mei</au><au>Huang, Yong</au><au>Wei, Jia-lin</au><au>Yang, Dong-lin</au><au>Feng, Si-zhou</au><au>Han, Ming-zhe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical study on acute kidney injury after myeloablative allogeneic hematopoietic cell transplantation</atitle><jtitle>Zhōnghuá xuèyèxué zázhì</jtitle><addtitle>Zhonghua Xue Ye Xue Za Zhi</addtitle><date>2008-06</date><risdate>2008</risdate><volume>29</volume><issue>6</issue><spage>401</spage><epage>404</epage><pages>401-404</pages><issn>0253-2727</issn><abstract>To explore the incidence, pathogenesis, risk factors, prophylaxis and treatment of acute kidney injury (AKI) after myeloablative allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Clinical data of 120 patients received myeloablative allo-HSCT were retrospectively analyzed.
Serum creatinine level in the patients showed significantly higher than baseline value at 28-60 days after transplantation (P<0.05). 73 patients (60.8%) developed AKI at a median of 33 days after allo-HSCT, including grade 2 in 32 patients (26.7%). Patients with grade 1 AKI showed significant higher serum cyclosporine A (CsA) levels (P<0.05). Hepatic veno-occlusive disease( HVOD), acute graft-versus-host disease (aGVHD) and total bilirubin > 40 micromol/L were high risk factors of occurring AKI (P<0.05). 19 patients died within 100 days after allo-HSCT, grade 2 AKI was a high risk factor of mortality (P< 0.05). 180-day survival rate was significantly lower in patients with grade 2 AKI after allo-HSCT (P<0.05).
AKI is one of the</abstract><cop>China</cop><pmid>19031744</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0253-2727 |
| ispartof | Zhōnghuá xuèyèxué zázhì, 2008-06, Vol.29 (6), p.401-404 |
| issn | 0253-2727 |
| language | chi |
| recordid | cdi_proquest_miscellaneous_733861652 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Acute Kidney Injury - etiology Acute Kidney Injury - prevention & control Adolescent Adult Female Hematopoietic Stem Cell Transplantation Humans Male Middle Aged Postoperative Complications - prevention & control Retrospective Studies Risk Factors Transplantation Conditioning Transplantation, Homologous Young Adult |
| title | Clinical study on acute kidney injury after myeloablative allogeneic hematopoietic cell transplantation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T19%3A05%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20study%20on%20acute%20kidney%20injury%20after%20myeloablative%20allogeneic%20hematopoietic%20cell%20transplantation&rft.jtitle=Zh%C5%8Dnghu%C3%A1%20xu%C3%A8y%C3%A8xu%C3%A9%20z%C3%A1zh%C3%AC&rft.au=Bao,%20Yu-shi&rft.date=2008-06&rft.volume=29&rft.issue=6&rft.spage=401&rft.epage=404&rft.pages=401-404&rft.issn=0253-2727&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E733861652%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=733861652&rft_id=info:pmid/19031744&rfr_iscdi=true |