Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer
Purpose To evaluate single photon emission computed tomography (SPECT)/spiral computed tomography (CT) fusion imaging for the diagnosis of bone metastasis in patients with known cancer and to compare the diagnostic efficacy of SPECT/CT fusion imaging with that of SPECT alone and with SPECT + CT. Mat...
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| Veröffentlicht in: | Skeletal radiology 2010-02, Vol.39 (2), p.147-153 |
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| creator | Zhao, Zhen Li, Lin Li, Fanglan Zhao, Lixia |
| description | Purpose
To evaluate single photon emission computed tomography (SPECT)/spiral computed tomography (CT) fusion imaging for the diagnosis of bone metastasis in patients with known cancer and to compare the diagnostic efficacy of SPECT/CT fusion imaging with that of SPECT alone and with SPECT + CT.
Materials and methods
One hundred forty-one bone lesions of 125 cancer patients (with nonspecific bone findings on bone scintigraphy) were investigated in the study. SPECT, CT, and SPECT/CT fusion images were acquired simultaneously. All images were interpreted independently by two experienced nuclear medicine physicians. In cases of discrepancy, consensus was obtained by a joint reading. The final diagnosis was based on biopsy proof and radiologic follow-up over at least 1 year.
Results
The final diagnosis revealed 63 malignant bone lesions and 78 benign lesions. The diagnostic sensitivity of SPECT, SPECT + CT, and SPECT/CT fusion imaging for malignant lesions was 82.5%, 93.7%, and 98.4%, respectively. Specificity was 66.7%, 80.8%, and 93.6%, respectively. Accuracy was 73.8%, 86.5%, and 95.7%, respectively. The specificity and accuracy of SPECT/CT fusion imaging for the diagnosis malignant bone lesions were significantly higher than those of SPECT alone and of SPECT + CT (
P
|
| doi_str_mv | 10.1007/s00256-009-0764-0 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_733861380</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A730797070</galeid><sourcerecordid>A730797070</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498t-d406310c2b64cc692f7c3eb7370a2f2fbf101fbb7dd82276a1c0af2b8101c24b3</originalsourceid><addsrcrecordid>eNp9kl1v1iAUxxujcXP6AbwxxEW96nZ4KbSXy-JbssQL9ZpQCn2YLVSgWfZJ_LpSnycummkggRx-_wOc86-q5xjOMIA4TwCk4TVAV4PgrIYH1TFmlNQEc_ywOgZagoSy9qh6ktI1ABai4Y-rI9xx3mHaHFc_Pjs_TgYtu5CDR2Z2Kbmy0WFe1mwGlMMcxqiW3e15WlxU031HyK6_VG5WY8mHbIgo7wwanBp9SC6hYFEfvEGzySqVWULOo0VlZ3xO6MblHfrmw025WXlt4tPqkVVTMs8O60n19d3bL5cf6qtP7z9eXlzVmnVtrgcGnGLQpOdMa94RKzQ1vaACFLHE9hYDtn0vhqElRHCFNShL-raENWE9Pane7PMuMXxfTcqyVECbaVLehDVJQWnLMW2hkK__SxJMmoawDXz5F3gd1ujLLySBFjeibUSBTvfQqCYjnbchR6W3jPJCUBCdALGlOruHKmMojdKlntaV-B8CvBfoGFKKxsollqbEW4lBbp6Re8_I4hm5eUZumheH9679bIY7xcEkBXh1AFTSarKxdMil31ypK2PASOHInkvlyI8m3n3837f_BIQG2rM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>208157857</pqid></control><display><type>article</type><title>Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Zhao, Zhen ; Li, Lin ; Li, Fanglan ; Zhao, Lixia</creator><creatorcontrib>Zhao, Zhen ; Li, Lin ; Li, Fanglan ; Zhao, Lixia</creatorcontrib><description>Purpose
To evaluate single photon emission computed tomography (SPECT)/spiral computed tomography (CT) fusion imaging for the diagnosis of bone metastasis in patients with known cancer and to compare the diagnostic efficacy of SPECT/CT fusion imaging with that of SPECT alone and with SPECT + CT.
Materials and methods
One hundred forty-one bone lesions of 125 cancer patients (with nonspecific bone findings on bone scintigraphy) were investigated in the study. SPECT, CT, and SPECT/CT fusion images were acquired simultaneously. All images were interpreted independently by two experienced nuclear medicine physicians. In cases of discrepancy, consensus was obtained by a joint reading. The final diagnosis was based on biopsy proof and radiologic follow-up over at least 1 year.
Results
The final diagnosis revealed 63 malignant bone lesions and 78 benign lesions. The diagnostic sensitivity of SPECT, SPECT + CT, and SPECT/CT fusion imaging for malignant lesions was 82.5%, 93.7%, and 98.4%, respectively. Specificity was 66.7%, 80.8%, and 93.6%, respectively. Accuracy was 73.8%, 86.5%, and 95.7%, respectively. The specificity and accuracy of SPECT/CT fusion imaging for the diagnosis malignant bone lesions were significantly higher than those of SPECT alone and of SPECT + CT (
P
< 0.05). Among 37 equivocal lesions revealed with SPECT, the diagnostic accuracy of bone lesions was 45.9% for SPECT + CT and 81.1% for SPECT/CT fusion imaging (χ
2
= 9.855,
P
= 0.002). The numbers of equivocal lesions were 37, 18, and 5 for SPECT, SPECT + CT, and SPECT/CT fusion imaging, respectively, and 29.7% (11/37), 27.8% (5/18), and 20.0% (1/5) of lesions were confirmed to be malignant by radiologic follow-up over at least 1 year.
Conclusions
SPECT/spiral CT is particularly valuable for the diagnosis of bone metastasis in patients with known cancer by providing precise anatomic localization and detailed morphologic characteristics.</description><identifier>ISSN: 0364-2348</identifier><identifier>EISSN: 1432-2161</identifier><identifier>DOI: 10.1007/s00256-009-0764-0</identifier><identifier>PMID: 19669135</identifier><identifier>CODEN: SKRADI</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Bone Neoplasms - diagnosis ; Bone Neoplasms - secondary ; Care and treatment ; CT imaging ; Diagnosis ; Diseases of the osteoarticular system ; Female ; Humans ; Imaging ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical imaging equipment ; Medical research ; Medical sciences ; Medicine & Public Health ; Medicine, Experimental ; Metastasis ; Middle Aged ; Nuclear Medicine ; Orthopedics ; Osteoarticular system. Muscles ; Pathology ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Radiology ; Reproducibility of Results ; Scientific Article ; Sensitivity and Specificity ; SPECT imaging ; Subtraction Technique ; Tomography, Emission-Computed, Single-Photon - methods ; Tomography, Spiral Computed - methods ; Tumors of striated muscle and skeleton</subject><ispartof>Skeletal radiology, 2010-02, Vol.39 (2), p.147-153</ispartof><rights>ISS 2009</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2010 Springer</rights><rights>ISS 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498t-d406310c2b64cc692f7c3eb7370a2f2fbf101fbb7dd82276a1c0af2b8101c24b3</citedby><cites>FETCH-LOGICAL-c498t-d406310c2b64cc692f7c3eb7370a2f2fbf101fbb7dd82276a1c0af2b8101c24b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00256-009-0764-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00256-009-0764-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22744042$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19669135$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhao, Zhen</creatorcontrib><creatorcontrib>Li, Lin</creatorcontrib><creatorcontrib>Li, Fanglan</creatorcontrib><creatorcontrib>Zhao, Lixia</creatorcontrib><title>Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer</title><title>Skeletal radiology</title><addtitle>Skeletal Radiol</addtitle><addtitle>Skeletal Radiol</addtitle><description>Purpose
To evaluate single photon emission computed tomography (SPECT)/spiral computed tomography (CT) fusion imaging for the diagnosis of bone metastasis in patients with known cancer and to compare the diagnostic efficacy of SPECT/CT fusion imaging with that of SPECT alone and with SPECT + CT.
Materials and methods
One hundred forty-one bone lesions of 125 cancer patients (with nonspecific bone findings on bone scintigraphy) were investigated in the study. SPECT, CT, and SPECT/CT fusion images were acquired simultaneously. All images were interpreted independently by two experienced nuclear medicine physicians. In cases of discrepancy, consensus was obtained by a joint reading. The final diagnosis was based on biopsy proof and radiologic follow-up over at least 1 year.
Results
The final diagnosis revealed 63 malignant bone lesions and 78 benign lesions. The diagnostic sensitivity of SPECT, SPECT + CT, and SPECT/CT fusion imaging for malignant lesions was 82.5%, 93.7%, and 98.4%, respectively. Specificity was 66.7%, 80.8%, and 93.6%, respectively. Accuracy was 73.8%, 86.5%, and 95.7%, respectively. The specificity and accuracy of SPECT/CT fusion imaging for the diagnosis malignant bone lesions were significantly higher than those of SPECT alone and of SPECT + CT (
P
< 0.05). Among 37 equivocal lesions revealed with SPECT, the diagnostic accuracy of bone lesions was 45.9% for SPECT + CT and 81.1% for SPECT/CT fusion imaging (χ
2
= 9.855,
P
= 0.002). The numbers of equivocal lesions were 37, 18, and 5 for SPECT, SPECT + CT, and SPECT/CT fusion imaging, respectively, and 29.7% (11/37), 27.8% (5/18), and 20.0% (1/5) of lesions were confirmed to be malignant by radiologic follow-up over at least 1 year.
Conclusions
SPECT/spiral CT is particularly valuable for the diagnosis of bone metastasis in patients with known cancer by providing precise anatomic localization and detailed morphologic characteristics.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Bone Neoplasms - diagnosis</subject><subject>Bone Neoplasms - secondary</subject><subject>Care and treatment</subject><subject>CT imaging</subject><subject>Diagnosis</subject><subject>Diseases of the osteoarticular system</subject><subject>Female</subject><subject>Humans</subject><subject>Imaging</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical imaging equipment</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Medicine & Public Health</subject><subject>Medicine, Experimental</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>Orthopedics</subject><subject>Osteoarticular system. Muscles</subject><subject>Pathology</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Scientific Article</subject><subject>Sensitivity and Specificity</subject><subject>SPECT imaging</subject><subject>Subtraction Technique</subject><subject>Tomography, Emission-Computed, Single-Photon - methods</subject><subject>Tomography, Spiral Computed - methods</subject><subject>Tumors of striated muscle and skeleton</subject><issn>0364-2348</issn><issn>1432-2161</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kl1v1iAUxxujcXP6AbwxxEW96nZ4KbSXy-JbssQL9ZpQCn2YLVSgWfZJ_LpSnycummkggRx-_wOc86-q5xjOMIA4TwCk4TVAV4PgrIYH1TFmlNQEc_ywOgZagoSy9qh6ktI1ABai4Y-rI9xx3mHaHFc_Pjs_TgYtu5CDR2Z2Kbmy0WFe1mwGlMMcxqiW3e15WlxU031HyK6_VG5WY8mHbIgo7wwanBp9SC6hYFEfvEGzySqVWULOo0VlZ3xO6MblHfrmw025WXlt4tPqkVVTMs8O60n19d3bL5cf6qtP7z9eXlzVmnVtrgcGnGLQpOdMa94RKzQ1vaACFLHE9hYDtn0vhqElRHCFNShL-raENWE9Pane7PMuMXxfTcqyVECbaVLehDVJQWnLMW2hkK__SxJMmoawDXz5F3gd1ujLLySBFjeibUSBTvfQqCYjnbchR6W3jPJCUBCdALGlOruHKmMojdKlntaV-B8CvBfoGFKKxsollqbEW4lBbp6Re8_I4hm5eUZumheH9679bIY7xcEkBXh1AFTSarKxdMil31ypK2PASOHInkvlyI8m3n3837f_BIQG2rM</recordid><startdate>20100201</startdate><enddate>20100201</enddate><creator>Zhao, Zhen</creator><creator>Li, Lin</creator><creator>Li, Fanglan</creator><creator>Zhao, Lixia</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20100201</creationdate><title>Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer</title><author>Zhao, Zhen ; Li, Lin ; Li, Fanglan ; Zhao, Lixia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-d406310c2b64cc692f7c3eb7370a2f2fbf101fbb7dd82276a1c0af2b8101c24b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Bone Neoplasms - diagnosis</topic><topic>Bone Neoplasms - secondary</topic><topic>Care and treatment</topic><topic>CT imaging</topic><topic>Diagnosis</topic><topic>Diseases of the osteoarticular system</topic><topic>Female</topic><topic>Humans</topic><topic>Imaging</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical imaging equipment</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Medicine & Public Health</topic><topic>Medicine, Experimental</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>Orthopedics</topic><topic>Osteoarticular system. Muscles</topic><topic>Pathology</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Radiology</topic><topic>Reproducibility of Results</topic><topic>Scientific Article</topic><topic>Sensitivity and Specificity</topic><topic>SPECT imaging</topic><topic>Subtraction Technique</topic><topic>Tomography, Emission-Computed, Single-Photon - methods</topic><topic>Tomography, Spiral Computed - methods</topic><topic>Tumors of striated muscle and skeleton</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhao, Zhen</creatorcontrib><creatorcontrib>Li, Lin</creatorcontrib><creatorcontrib>Li, Fanglan</creatorcontrib><creatorcontrib>Zhao, Lixia</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Skeletal radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhao, Zhen</au><au>Li, Lin</au><au>Li, Fanglan</au><au>Zhao, Lixia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer</atitle><jtitle>Skeletal radiology</jtitle><stitle>Skeletal Radiol</stitle><addtitle>Skeletal Radiol</addtitle><date>2010-02-01</date><risdate>2010</risdate><volume>39</volume><issue>2</issue><spage>147</spage><epage>153</epage><pages>147-153</pages><issn>0364-2348</issn><eissn>1432-2161</eissn><coden>SKRADI</coden><abstract>Purpose
To evaluate single photon emission computed tomography (SPECT)/spiral computed tomography (CT) fusion imaging for the diagnosis of bone metastasis in patients with known cancer and to compare the diagnostic efficacy of SPECT/CT fusion imaging with that of SPECT alone and with SPECT + CT.
Materials and methods
One hundred forty-one bone lesions of 125 cancer patients (with nonspecific bone findings on bone scintigraphy) were investigated in the study. SPECT, CT, and SPECT/CT fusion images were acquired simultaneously. All images were interpreted independently by two experienced nuclear medicine physicians. In cases of discrepancy, consensus was obtained by a joint reading. The final diagnosis was based on biopsy proof and radiologic follow-up over at least 1 year.
Results
The final diagnosis revealed 63 malignant bone lesions and 78 benign lesions. The diagnostic sensitivity of SPECT, SPECT + CT, and SPECT/CT fusion imaging for malignant lesions was 82.5%, 93.7%, and 98.4%, respectively. Specificity was 66.7%, 80.8%, and 93.6%, respectively. Accuracy was 73.8%, 86.5%, and 95.7%, respectively. The specificity and accuracy of SPECT/CT fusion imaging for the diagnosis malignant bone lesions were significantly higher than those of SPECT alone and of SPECT + CT (
P
< 0.05). Among 37 equivocal lesions revealed with SPECT, the diagnostic accuracy of bone lesions was 45.9% for SPECT + CT and 81.1% for SPECT/CT fusion imaging (χ
2
= 9.855,
P
= 0.002). The numbers of equivocal lesions were 37, 18, and 5 for SPECT, SPECT + CT, and SPECT/CT fusion imaging, respectively, and 29.7% (11/37), 27.8% (5/18), and 20.0% (1/5) of lesions were confirmed to be malignant by radiologic follow-up over at least 1 year.
Conclusions
SPECT/spiral CT is particularly valuable for the diagnosis of bone metastasis in patients with known cancer by providing precise anatomic localization and detailed morphologic characteristics.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>19669135</pmid><doi>10.1007/s00256-009-0764-0</doi><tpages>7</tpages></addata></record> |
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| ispartof | Skeletal radiology, 2010-02, Vol.39 (2), p.147-153 |
| issn | 0364-2348 1432-2161 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Bone Neoplasms - diagnosis Bone Neoplasms - secondary Care and treatment CT imaging Diagnosis Diseases of the osteoarticular system Female Humans Imaging Investigative techniques, diagnostic techniques (general aspects) Male Medical imaging equipment Medical research Medical sciences Medicine & Public Health Medicine, Experimental Metastasis Middle Aged Nuclear Medicine Orthopedics Osteoarticular system. Muscles Pathology Radiodiagnosis. Nmr imagery. Nmr spectrometry Radiology Reproducibility of Results Scientific Article Sensitivity and Specificity SPECT imaging Subtraction Technique Tomography, Emission-Computed, Single-Photon - methods Tomography, Spiral Computed - methods Tumors of striated muscle and skeleton |
| title | Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer |
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