Genetic polymorphisms in the dopamine-2 receptor ( DRD2), dopamine-3 receptor ( DRD3), and dopamine transporter ( SLC6A3) genes in schizophrenia: Data from an association study

To investigate the association between dopaminergic polymorphisms [ DRD2 −141C Ins/Del, DRD3 Ser9Gly, and SLC6A3 VNTR] and schizophrenia. Two hundred and eighty-eight outpatients with schizophrenia (DSM-IV criteria) [mean age (SD) = 36.4 (12.4), 60.1% males] and 421 unrelated healthy controls [mean...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2010-02, Vol.34 (1), p.26-31
Hauptverfasser:	Sáiz, Pilar A., García-Portilla, M. Paz, Arango, Celso, Morales, Blanca, Arias, Bárbara, Corcoran, Paul, Fernández, Juan M., Alvarez, Victoria, Coto, Eliecer, Bascarán, María-Teresa, Bousoño, Manuel, Fañanas, Lourdes, Bobes, Julio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Biological and medical sciences Case-Control Studies Chi-Square Distribution Dopamine D2 receptor Dopamine D3 receptor Dopamine Plasma Membrane Transport Proteins - genetics Dopamine transporter Female Gene Frequency Genetic association Genetic Predisposition to Disease Genome-Wide Association Study - methods Genotype Humans Male Medical sciences Middle Aged Minisatellite Repeats - genetics Neuropharmacology Pharmacology. Drug treatments Polymorphism, Genetic - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Receptors, Dopamine D2 - genetics Receptors, Dopamine D3 - genetics Schizophrenia Schizophrenia - genetics Spain Young Adult
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