Giant Lysosomes in the Renal Proximal Tubules - A Morphological Characteristic of DBA/2 and DBA/1 Mouse Kidneys
The DBA/2Cr mouse is characterized by the presence of giant lysosomes located in the proximal convoluted tubules of males and proximal straight tubules of females. However, it remains unclear whether these giant lysosomes in the proximal tubules are characteristic of DBA/2Cr specifically, or are com...
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Veröffentlicht in: | Experimental Animals 2003, Vol.52(2), pp.159-163 |
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creator | YABUKI, Akira MATSUMOTO, Mitsuharu NISHINAKAGAWA, Hayao SUZUKI, Syusaku |
description | The DBA/2Cr mouse is characterized by the presence of giant lysosomes located in the proximal convoluted tubules of males and proximal straight tubules of females. However, it remains unclear whether these giant lysosomes in the proximal tubules are characteristic of DBA/2Cr specifically, or are common to other DBA/2 substrains and DBA/1. The present study investigated the morphology of kidneys from DBA/2CrSlc, DBA/2JJcl, DBA/2NCrj and DBA/1JNCrj mice of both sexes. Giant lysosomes in the renal proximal tubules were found to represent common morphological characteristic of both DBA/2 and DBA/1JN. |
doi_str_mv | 10.1538/expanim.52.159 |
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However, it remains unclear whether these giant lysosomes in the proximal tubules are characteristic of DBA/2Cr specifically, or are common to other DBA/2 substrains and DBA/1. The present study investigated the morphology of kidneys from DBA/2CrSlc, DBA/2JJcl, DBA/2NCrj and DBA/1JNCrj mice of both sexes. Giant lysosomes in the renal proximal tubules were found to represent common morphological characteristic of both DBA/2 and DBA/1JN.</description><identifier>ISSN: 1341-1357</identifier><identifier>EISSN: 1881-7122</identifier><identifier>DOI: 10.1538/expanim.52.159</identifier><identifier>PMID: 12806891</identifier><language>eng</language><publisher>Japan: Japanese Association for Laboratory Animal Science</publisher><subject>Animals ; DBA/1 ; DBA/2 ; Female ; giant lysosomes ; kidney ; Kidney Tubules, Proximal - anatomy & histology ; Kidney Tubules, Proximal - ultrastructure ; Lysosomes - ultrastructure ; Male ; Mice ; Mice, Inbred DBA</subject><ispartof>Experimental Animals, 2003, Vol.52(2), pp.159-163</ispartof><rights>2003 Japanese Association for Laboratory Animal Science</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-7fa8fd4a3d132f16c914d9022782d0163b2886401cfb4e942e7d17a2056623c3</citedby><cites>FETCH-LOGICAL-c495t-7fa8fd4a3d132f16c914d9022782d0163b2886401cfb4e942e7d17a2056623c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1876,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12806891$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>YABUKI, Akira</creatorcontrib><creatorcontrib>MATSUMOTO, Mitsuharu</creatorcontrib><creatorcontrib>NISHINAKAGAWA, Hayao</creatorcontrib><creatorcontrib>SUZUKI, Syusaku</creatorcontrib><title>Giant Lysosomes in the Renal Proximal Tubules - A Morphological Characteristic of DBA/2 and DBA/1 Mouse Kidneys</title><title>Experimental Animals</title><addtitle>Exp Anim</addtitle><description>The DBA/2Cr mouse is characterized by the presence of giant lysosomes located in the proximal convoluted tubules of males and proximal straight tubules of females. However, it remains unclear whether these giant lysosomes in the proximal tubules are characteristic of DBA/2Cr specifically, or are common to other DBA/2 substrains and DBA/1. The present study investigated the morphology of kidneys from DBA/2CrSlc, DBA/2JJcl, DBA/2NCrj and DBA/1JNCrj mice of both sexes. Giant lysosomes in the renal proximal tubules were found to represent common morphological characteristic of both DBA/2 and DBA/1JN.</description><subject>Animals</subject><subject>DBA/1</subject><subject>DBA/2</subject><subject>Female</subject><subject>giant lysosomes</subject><subject>kidney</subject><subject>Kidney Tubules, Proximal - anatomy & histology</subject><subject>Kidney Tubules, Proximal - ultrastructure</subject><subject>Lysosomes - ultrastructure</subject><subject>Male</subject><subject>Mice</subject><subject>Mice, Inbred DBA</subject><issn>1341-1357</issn><issn>1881-7122</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkEtv2zAQhIkiRfO85hjwlJsc7lISqaPjvIq6aFH4LtDUKmYgiQ4pAfG_D1sbaS7kLObjYDmMXYKYQSH1Db1tzeD6WYFprr6wE9AaMgWIR0nLHDKQhTpmpzG-CIFKYfWNHQNqUeoKTph_dGYY-XIXffQ9Re4GPm6I_6HBdPx38G-uT2I1racuuRmf858-bDe-88_OJmexMcHYkYKLo7Pct_zudn6D3AzNPwWJnyLxH64ZaBfP2dfWdJEuDvcZWz3crxZP2fLX4_fFfJnZvCrGTLVGt01uZAMSWyhtBXlTCUSlsRFQyjVqXeYCbLvOqcqRVAPKoCjKEqWVZ-x6H7sN_nWiONa9i5a6zgyU1qmVlLqQZZnA2R60wccYqK23If047GoQ9d-G60PDdYFprtKDq0PytO6p-Y8fKk3AYg-8xNE80wdgQuqno895uD9S7IdrU501DfIdyW6PZA</recordid><startdate>20030401</startdate><enddate>20030401</enddate><creator>YABUKI, Akira</creator><creator>MATSUMOTO, Mitsuharu</creator><creator>NISHINAKAGAWA, Hayao</creator><creator>SUZUKI, Syusaku</creator><general>Japanese Association for Laboratory Animal Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20030401</creationdate><title>Giant Lysosomes in the Renal Proximal Tubules - A Morphological Characteristic of DBA/2 and DBA/1 Mouse Kidneys</title><author>YABUKI, Akira ; MATSUMOTO, Mitsuharu ; NISHINAKAGAWA, Hayao ; SUZUKI, Syusaku</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-7fa8fd4a3d132f16c914d9022782d0163b2886401cfb4e942e7d17a2056623c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Animals</topic><topic>DBA/1</topic><topic>DBA/2</topic><topic>Female</topic><topic>giant lysosomes</topic><topic>kidney</topic><topic>Kidney Tubules, Proximal - anatomy & histology</topic><topic>Kidney Tubules, Proximal - ultrastructure</topic><topic>Lysosomes - ultrastructure</topic><topic>Male</topic><topic>Mice</topic><topic>Mice, Inbred DBA</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>YABUKI, Akira</creatorcontrib><creatorcontrib>MATSUMOTO, Mitsuharu</creatorcontrib><creatorcontrib>NISHINAKAGAWA, Hayao</creatorcontrib><creatorcontrib>SUZUKI, Syusaku</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental Animals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>YABUKI, Akira</au><au>MATSUMOTO, Mitsuharu</au><au>NISHINAKAGAWA, Hayao</au><au>SUZUKI, Syusaku</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Giant Lysosomes in the Renal Proximal Tubules - A Morphological Characteristic of DBA/2 and DBA/1 Mouse Kidneys</atitle><jtitle>Experimental Animals</jtitle><addtitle>Exp Anim</addtitle><date>2003-04-01</date><risdate>2003</risdate><volume>52</volume><issue>2</issue><spage>159</spage><epage>163</epage><pages>159-163</pages><issn>1341-1357</issn><eissn>1881-7122</eissn><abstract>The DBA/2Cr mouse is characterized by the presence of giant lysosomes located in the proximal convoluted tubules of males and proximal straight tubules of females. However, it remains unclear whether these giant lysosomes in the proximal tubules are characteristic of DBA/2Cr specifically, or are common to other DBA/2 substrains and DBA/1. The present study investigated the morphology of kidneys from DBA/2CrSlc, DBA/2JJcl, DBA/2NCrj and DBA/1JNCrj mice of both sexes. Giant lysosomes in the renal proximal tubules were found to represent common morphological characteristic of both DBA/2 and DBA/1JN.</abstract><cop>Japan</cop><pub>Japanese Association for Laboratory Animal Science</pub><pmid>12806891</pmid><doi>10.1538/expanim.52.159</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Animals DBA/1 DBA/2 Female giant lysosomes kidney Kidney Tubules, Proximal - anatomy & histology Kidney Tubules, Proximal - ultrastructure Lysosomes - ultrastructure Male Mice Mice, Inbred DBA |
title | Giant Lysosomes in the Renal Proximal Tubules - A Morphological Characteristic of DBA/2 and DBA/1 Mouse Kidneys |
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